Bile Duct Cancer Clinical Trials

22 recruiting

Frequently Asked Questions

Common questions about Bile Duct Cancer clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 22 trials

Recruiting
Phase 1

Pressurized Intraperitoneal Aerosolized Nab-Paclitaxel in Combination With Gemcitabine and Cisplatin for the Treatment of Biliary Tract Cancer Patients With Peritoneal Metastases

Intrahepatic CholangiocarcinomaGallbladder CarcinomaMetastatic Malignant Neoplasm in the Peritoneum+5 more
City of Hope Medical Center12 enrolled1 locationNCT05285358
Recruiting
Phase 2

PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma

Colorectal, CancerCholangiocarcinomaColorectal Neoplasms+10 more
National Cancer Institute (NCI)70 enrolled1 locationNCT05286814
Recruiting
Not Applicable

Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes

Liver CancerBiliary Tract CancerColon Cancer+76 more
Cedars-Sinai Medical Center360 enrolled1 locationNCT04907643
Recruiting
Phase 1Phase 2

A Study of CDX-1140, a CD40 Agonist, in Combination With Capecitabine and Oxaliplatin (CAPOX) and Keytruda in Subjects With Biliary Tract Carcinoma (BTC)

Biliary CancerBile Duct CancerCancer of the Bile Duct
National Cancer Institute (NCI)60 enrolled1 locationNCT05849480
Recruiting

Obtaining Solid Tumor Tissue From People Having Biopsy or Surgery for Certain Types of Cancer

CholangiocarcinomaPancreas CancerColorectal Neoplasms+2 more
National Cancer Institute (NCI)1,800 enrolled1 locationNCT01915225
Recruiting
Phase 2

Study of Gemcitabine, Cisplatin, AB680 and AB122 During First Line Treatment of Advanced Biliary Tract Cancers (QUIC)

CholangiocarcinomaBile Duct CancerBiliary Tract Carcinoma
Nataliya Uboha33 enrolled4 locationsNCT06048133
Recruiting

Integrated Cancer Repository for Cancer Research

Breast CancerLiver CancerEsophageal Cancer+47 more
University of Nebraska999,999 enrolled45 locationsNCT02012699
Recruiting
Phase 3

Tissue Adhesive Glue Modified Cyanoacrylate (Glubran® 2) in Soft Pancreas

Pancreatic CancerCholangiocarcinomaPancreatic Ductal Adenocarcinoma+4 more
Minia University194 enrolled1 locationNCT07155525
Recruiting
Not Applicable

Liver Transplantation for Non-resectable Perihilar Cholangiocarcinoma

Bile Duct CancerPerihilar CholangiocarcinomaKlatskin Tumor
Oslo University Hospital15 enrolled1 locationNCT04993131
Recruiting
Phase 1

Intraperitoneal Aerosolized Nanoliposomal Irinotecan (Nal-IRI) in Peritoneal Carcinomatosis From Gastrointestinal Cancer

Colorectal, CancerPancreatic CancerGastric Cancer+5 more
University Hospital, Ghent45 enrolled1 locationNCT05277766
Recruiting

Evaluation of diagnostiC Capacity of eccDNAs as Biomarkers in Indetermined biLiary Stricture(ECCBILE)

Pancreas CancerBile Duct CancerBiliary Stricture
Peking University Third Hospital99 enrolled2 locationsNCT06277531
Recruiting
Phase 2

Additional Chemotherapy Administered Directly Into the Liver Using a Chemo Pump in Patients With Bile Duct Cancer Inside the Liver Treatable by Surgery

Intrahepatic Cholangiocarcinoma (Icc)Intrahepatic Bile Duct CancerIntrahepatic Bile Duct Carcinoma+1 more
Erasmus Medical Center40 enrolled1 locationNCT06888063
Recruiting
Phase 2

Y-90 With Durvalumab/Gem/Cis in Intrahepatic Cholangio

CholangiocarcinomaBile Duct CancerCholangiocarcinoma Non-resectable+2 more
Beth Israel Deaconess Medical Center30 enrolled1 locationNCT05655949
Recruiting

Spanish Registry of Digestive Tumours RETUD

Pancreatic CancerRectal CancerBile Duct Cancer+3 more
Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)20,000 enrolled1 locationNCT06711211
Recruiting
Phase 1

Phase 1 Study of UCMYM802 Injection in Mesothelin-positive Advanced Malignant Solid Tumors

Breast Cancer FemaleColorectal, CancerPancreatic Cancer+4 more
UTC Therapeutics Inc.24 enrolled1 locationNCT06256055
Recruiting
Phase 2

AZD6738 Plus Durvalumab in Biliary Tract Cancer

Chemotherapy EffectBile Duct Cancer
Seoul National University Hospital26 enrolled1 locationNCT04298008
Recruiting

Quebec Pancreas Cancer Study

Pancreatic CancerPancreas CancerHereditary Cancer+8 more
George Zogopoulos2,000 enrolled1 locationNCT04104230
Recruiting
Not Applicable

EUS Examination Using EndoSound Vision System vs. Standard Echoendoscope

Pancreatic CancerGastrointestinal CancerBile Duct Cancer+6 more
Orlando Health, Inc.140 enrolled1 locationNCT06340620
Recruiting
Phase 1

A Clinical Trial Targeting CEA Chimeric Antigen Receptor T (CAR-T) for CEA Positive Advanced Malignant Solid Tumors

Breast CancerColorectal, CancerGastric Cancer+4 more
Chongqing Precision Biotech Co., Ltd30 enrolled2 locationsNCT06043466
Recruiting

A Study on the Prevalence of Clinically Useful Mutations in Solid Tumor Characterized by Next Generation Sequencing Methods on Liquid Biopsy Analysis (POPCORN)

Breast CancerPancreatic CancerGastric Cancer+11 more
Centro di Riferimento Oncologico - Aviano782 enrolled1 locationNCT06028724