Depression Clinical Trials in Bethesda, Maryland
12 recruitingBethesda, Maryland
Showing 1–12 of 12 trials
Recruiting
Phase 1
PET Imaging of Cyclooxygenase in Participants With Major Depressive Disorder (MDD)
Depression
National Institute of Mental Health (NIMH)64 enrolled1 locationNCT04582916
Recruiting
NIMH Rhythms and Blues Study: A Prospective Natural History Study of Motor Activity, Mood States, and Bipolar Disorder
MigraineMajor DepressionBipolar Disorder
National Institute of Mental Health (NIMH)1,260 enrolled1 locationNCT05669703
Recruiting
Characterization and Treatment of Adolescent Depression
Depression
National Institute of Mental Health (NIMH)4,100 enrolled1 locationNCT03388606
Recruiting
Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers
DepressionHealthy VolunteersAnxiety Disorders+2 more
National Institute of Mental Health (NIMH)16,000 enrolled1 locationNCT00024635
Recruiting
Phase 1
Mechanism of Action Underlying Ketamine's Antidepressant Effects: The AMPA Throughput Theory in Patients With Treatment-Resistant Major Depression
DepressionMajor Depressive DisorderMajor Depression
National Institute of Mental Health (NIMH)70 enrolled1 locationNCT03973268
Recruiting
Natural History of Depression, Bipolar Disorder and Suicide Risk
Molecular Mechanisms of Pharmacological ActionDepressive SymptomsSuicide+18 more
National Institute of Mental Health (NIMH)500 enrolled1 locationNCT06462196
Recruiting
Phase 2
Neurobiology of Suicide
DepressionHealthy Volunteers
National Institute of Mental Health (NIMH)325 enrolled1 locationNCT02543983
Recruiting
Phase 1
Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder
DepressionHealthy VolunteerMajor Depressive Disorder
National Institute of Mental Health (NIMH)150 enrolled1 locationNCT03065335
Recruiting
Phase 2
Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression
DepressionDepressive DisorderMolecular Mechanisms of Pharmacological Action+10 more
National Institute of Mental Health (NIMH)50 enrolled1 locationNCT06511908
Recruiting
Not Applicable
CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms
InsomniaTraumatic Brain InjuryDepression+7 more
Johns Hopkins University360 enrolled5 locationsNCT05663034
Recruiting
Phase 1
[18F]PF-06445974 to Image PDE4B in Major Depressive Disorder Using PET
Depression
National Institute of Mental Health (NIMH)108 enrolled1 locationNCT05703685
Recruiting
Long-term Observation of Participants With Mood Disorders
DepressionSuicide Risk
National Institute of Mental Health (NIMH)1,000 enrolled1 locationNCT04877977