Metastatic Cancer Clinical Trials

3 recruiting

Showing 119 of 19 trials

Recruiting
Phase 1Phase 2

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

Ovarian CancerEndometrial CancerProstate Cancer+5 more
PMV Pharmaceuticals, Inc300 enrolled76 locationsNCT04585750
Recruiting
Phase 1

A Study to Learn About Study Medicine ALTA2618 in Adults With AKT1 E17K-Mutant Solid Tumors

Breast CancerEndometrial CancerAdvanced Solid Tumor+2 more
Alterome Therapeutics, Inc.110 enrolled51 locationsNCT06533059
Recruiting
Phase 1Phase 2

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

Advanced Solid TumorMetastatic CancerCutaneous Melanoma
Aulos Bioscience, Inc.159 enrolled17 locationsNCT05267626
Recruiting
Phase 2

Trial of Two Adagrasib Dosing Regimens in NSCLC With KRAS G12C Mutation (KRYSTAL 21)

Metastatic CancerAdvanced CancerMalignant Neoplasm of Lung
Mirati Therapeutics Inc.200 enrolled120 locationsNCT05853575
Recruiting
Phase 1

A Study of MGC026 in Participants With Advanced Solid Tumors

Advanced Solid TumorSquamous Cell Carcinoma of Head and NeckMetastatic Cancer+1 more
MacroGenics250 enrolled12 locationsNCT06242470
Recruiting
Phase 1Phase 2

Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer

Breast CancerBreast Cancer MetastaticOvarian Cancer+6 more
Incyclix Bio150 enrolled17 locationsNCT05735080
Recruiting
Phase 1

MEM-288 Oncolytic Virus Alone and in Combination With Standard of Care Therapy in Advanced Solid Tumors

Metastatic CancerAdvanced CancerSolid Tumor
Memgen, Inc.40 enrolled2 locationsNCT05076760
Recruiting
Not Applicable

PROGRESS: Precision Oncology Using Genomic Reflexive Evaluations for Study Selection and Survival

Breast CancerMetastatic CancerSolid Tumor Malignancies
UNC Lineberger Comprehensive Cancer Center500 enrolled1 locationNCT06896162
Recruiting
Phase 2

Definitive Radiation for High-Risk Spine Metastases

Metastatic Breast CancerMetastatic CancerMetastatic Lung Cancer+5 more
Stony Brook University26 enrolled1 locationNCT06165419
Recruiting
Phase 2

Biomarkers to Detect Endocrine Therapy Resistance

Breast CancerMetastatic CancerLobular Breast Carcinoma
University of Wisconsin, Madison8 enrolled1 locationNCT06067503
Recruiting
Phase 1

Phase 1 Trial of SYNC-T - Immunotherapy for Patients With Advanced/Metastatic Solid Tumors

Metastatic Breast CancerCancerMetastatic Cancer+2 more
Williams Cancer Foundation20 enrolled1 locationNCT05544240
Recruiting
Phase 1

PRE-I-SPY Phase I/Ib Oncology Platform Program

Metastatic Breast CancerHER2-negative Breast CancerMetastatic Cancer+5 more
QuantumLeap Healthcare Collaborative124 enrolled7 locationsNCT05868226
Recruiting

PSA Biochemical Response as Prognostic Factor in Metastatic Castration-Sensitive Prostate Cancer

Prostate CancerMetastatic CancerCastrate Sensitive Prostate Cancer
Fondazione Policlinico Universitario Agostino Gemelli IRCCS152 enrolled1 locationNCT06652607
Recruiting
Phase 2

COntinue the SaMe Systemic Therapy After Local Ablative Therapy for Oligo Progression in Metastatic Breast Cancer - the COSMO Study

Breast Cancer InvasiveMetastatic CancerOligoprogressive
The Netherlands Cancer Institute118 enrolled7 locationsNCT05301881
Recruiting
Phase 1Phase 2

A Study of OR502, a Monoclonal Antibody Targeting LILRB2, Alone and in Combination With Anticancer Agents

Advanced Solid TumorCancerNon-small Cell Lung Cancer+4 more
OncoResponse, Inc.168 enrolled4 locationsNCT06090266
Recruiting
Not Applicable

Comprehensive Outcomes for After Cancer Health

Breast CancerMetastatic Breast CancerGastric Cancer+8 more
Pack Health625 enrolled7 locationsNCT05349227
Recruiting
Phase 3

Metastasis-directed Therapy for Oligorecurrent Prostate Cancer

Prostate CancerMetastatic CancerProstate Cancer Metastatic+4 more
Universitaire Ziekenhuizen KU Leuven873 enrolled1 locationNCT05352178
Recruiting
Phase 2

Immune Therapy in HR-positive/HER2-negative Metastatic Breast Cancer(ENIGMA)-BCTOP-L-M02

Breast CancerMetastatic Cancer
Fudan University338 enrolled1 locationNCT05205200
Recruiting
Not Applicable

Metastases Directed Therapy for Oligometastatic Breast Cancer

Breast CancerMetastatic Breast CancerMetastatic Cancer
National Cancer Institute, Egypt150 enrolled1 locationNCT06144346