Clinical Trials in High Wycombe, United Kingdom

17 recruiting

Showing 120 of 20 trials

Recruiting
Phase 2

A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Chronic Kidney Disease

Chronic Kidney Disease
Boehringer Ingelheim416 enrolled153 locationsNCT06926660
Recruiting
Phase 3

A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure

Heart Failure
Boehringer Ingelheim6,000 enrolled652 locationsNCT06424288
Recruiting
Phase 3

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

Heart Failure and Impaired Kidney Function
AstraZeneca4,800 enrolled842 locationsNCT06307652
Recruiting
Phase 2

A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF)

Heart Failure
Pfizer620 enrolled125 locationsNCT06991257
Recruiting
Phase 2

A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy

Heart Failure
Novo Nordisk A/S200 enrolled109 locationsNCT06979362
Recruiting
Phase 2

A Research Study Comparing CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Reduced/Mildly Reduced Ejection Fraction and Left Ventricular Hypertrophy

Heart Failure
Novo Nordisk A/S200 enrolled92 locationsNCT06979375
Recruiting
Phase 3

A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation

Heart Failure
Novo Nordisk A/S5,600 enrolled1117 locationsNCT05636176
Recruiting
Not Applicable

RCT of Implantable Defibrillators in Patients With Non Ischemic Cardiomyopathy, Scar and Severe Systolic Heart Failure

Heart Failure
University Hospital Southampton NHS Foundation Trust2,504 enrolled47 locationsNCT05568069
Recruiting
Phase 3

A Study to Evaluate Astegolimab in Participants With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease (COPD)
Hoffmann-La Roche1,290 enrolled462 locationsNCT05595642
Recruiting
Phase 3

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

ObesityHeart Failure With Preserved Ejection FractionHeart Failure With Mildly Reduced Ejection Fraction
Amgen5,056 enrolled564 locationsNCT07037459
Recruiting
Phase 3

Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)

Atrial Fibrillation (AF)
Anthos Therapeutics, Inc.1,900 enrolled721 locationsNCT05712200
Recruiting
Phase 2

A Study to Assess the Efficacy and Safety of Verekitug in Participants With COPD

Chronic Obstructive Pulmonary Disease
Upstream Bio Inc.666 enrolled325 locationsNCT06981078
Recruiting

Audit of Targeted Sentinel Node Biopsy (TSNB) in Patients With Limited Nodal Disease Undergoing Primary Surgery

Breast CancerSentinel Lymph Node Biopsy (SLNB)Axillary Lymph Nodes Dissection+1 more
University Hospitals of Derby and Burton NHS Foundation Trust200 enrolled10 locationsNCT07085442
Recruiting
Phase 2

A Study to Evaluate Solrikitug in Participants With COPD (ZION)

COPD
Uniquity One (UNI)171 enrolled92 locationsNCT06496620
Recruiting
Not Applicable

Axillary Management in Breast Cancer Patients With Needle Biopsy Proven Nodal Metastases After Neoadjuvant Chemotherapy

Breast CancerSentinel Lymph NodeNeoplasm, Breast
University Hospitals of Derby and Burton NHS Foundation Trust1,900 enrolled98 locationsNCT04109079
Recruiting
Not Applicable

The Early Valve Replacement in Severe ASYmptomatic Aortic Stenosis Study

Aortic Stenosis
University of Leicester2,844 enrolled110 locationsNCT04204915
Recruiting
Not Applicable

Symptoms and Functions in Patients With COPD and Chronic Bronchitis Switching From CIG to THS

COPDSmokingTobacco Use
Philip Morris Products S.A.290 enrolled111 locationsNCT07108166
Recruiting
Not Applicable

Biological Matrices Versus Synthetic Meshes

Breast Cancer
University Hospitals of Derby and Burton NHS Foundation Trust60 enrolled5 locationsNCT05449691
Recruiting
Phase 2

Use of a Novel SUBCUTaneous Preparation of Furosemide to Facilitate Early Supported Discharge of Patients With Heart Failure

Heart Failure
NHS Greater Glasgow and Clyde170 enrolled22 locationsNCT05419115
Recruiting

Tracking Mutations in Cell Free Tumour DNA to Predict Relapse in Early Colorectal Cancer

Colorectal, Cancer
Royal Marsden NHS Foundation Trust1,000 enrolled71 locationsNCT04050345