Clinical Trials in Milton Keynes, United Kingdom

5 recruiting

Showing 111 of 11 trials

Recruiting
Phase 3

A Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004)

Non-small Cell Lung Cancer
Merck Sharp & Dohme LLC600 enrolled212 locationsNCT06345729
Recruiting
Phase 3

Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD), Characterized by an Eosinophilic Phenotype

Chronic Obstructive Pulmonary Disease
Sanofi942 enrolled150 locationsNCT07190222
Recruiting
Phase 2

A Study to Assess the Efficacy and Safety of Verekitug in Participants With COPD

Chronic Obstructive Pulmonary Disease
Upstream Bio Inc.666 enrolled325 locationsNCT06981078
Recruiting

Real-World Study to Assess Subcutaneous Epcoritamab in Adult Participants With Diffuse Large B-Cell and Follicular Lymphoma

Diffuse Large B Cell LymphomaFollicular Lymphoma
AbbVie700 enrolled73 locationsNCT06830759
Recruiting
Phase 3

MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide)

Multiple Myeloma
Pfizer492 enrolled273 locationsNCT06152575
Recruiting
Phase 3

Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation

Metastatic Breast Cancer
Sermonix Pharmaceuticals Inc.500 enrolled222 locationsNCT05696626
Recruiting
Not Applicable

Axillary Management in Breast Cancer Patients With Needle Biopsy Proven Nodal Metastases After Neoadjuvant Chemotherapy

Breast CancerSentinel Lymph NodeNeoplasm, Breast
University Hospitals of Derby and Burton NHS Foundation Trust1,900 enrolled98 locationsNCT04109079
Recruiting
Phase 2

Pembrolizumab With Olaparib as Combined Therapy in Metastatic Pancreatic Cancer

Pancreatic Cancer
Cambridge University Hospitals NHS Foundation Trust20 enrolled13 locationsNCT05093231
Recruiting
Phase 3

Supported Rescue Packs Post-discharge in Chronic Obstructive Pulmonary Disease

COPDCOPD Exacerbation
Guy's and St Thomas' NHS Foundation Trust1,400 enrolled34 locationsNCT06347536
Recruiting

Tracking Mutations in Cell Free Tumour DNA to Predict Relapse in Early Colorectal Cancer

Colorectal, Cancer
Royal Marsden NHS Foundation Trust1,000 enrolled71 locationsNCT04050345
Recruiting
Phase 3

The Role of Ixazomib in Autologous Stem Cell Transplant in Relapsed Myeloma - Myeloma XII (ACCoRd)

Multiple Myeloma
University of Leeds406 enrolled91 locationsNCT03562169