Clinical Trials in Nijmegen, Netherlands

6 recruiting

Showing 120 of 22 trials

Recruiting
Phase 2Phase 3

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

Advanced Non-Small Cell Lung Cancer
Mirati Therapeutics Inc.806 enrolled764 locationsNCT04613596
Recruiting
Phase 1

Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers

Non-small Cell Lung CancerPancreatic Ductal AdenocarcinomaHR+/HER2- Ductal and Lobular Breast Cancer
Novartis Pharmaceuticals162 enrolled30 locationsNCT06562192
Recruiting
Phase 3

A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

Merck Sharp & Dohme LLC680 enrolled225 locationsNCT06623422
Recruiting
Phase 3

A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

Prostate Cancer
AstraZeneca700 enrolled328 locationsNCT06952803
Recruiting

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

Breast CancerLiver CancerEsophageal Cancer+35 more
UMC Utrecht8,000 enrolled18 locationsNCT04075305
Recruiting
Phase 3

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

PIK3CA Mutation
Relay Therapeutics, Inc.540 enrolled76 locationsNCT06982521
Recruiting
Phase 3

A Study to Learn More About How Well Sevabertinib (BAY 2927088) Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

Bayer278 enrolled283 locationsNCT06452277
Recruiting
Phase 1

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

Breast NeoplasmsCholangiocarcinomaOvarian Neoplasms+4 more
Eli Lilly and Company241 enrolled27 locationsNCT07213791
Recruiting
Phase 2

A Study To Evaluate The Efficacy And Safety Of Ifinatamab Deruxtecan (I-DXd) In Subjects With Recurrent Or Metastatic Solid Tumors (IDeate-PanTumor02)

Recurrent or Metastatic Solid Tumors
Daiichi Sankyo520 enrolled119 locationsNCT06330064
Recruiting
Phase 3

A Study to Assess the Efficacy and Safety of Zipalertinib Versus Placebo for Adjuvant Treatment in Participants With Stage IB-IIIA NSCLC With Uncommon EGFR Mutations, Following Complete Tumor Resection

Lung CancerEGFRNSCLC, Stage IB-IIIA+5 more
Taiho Oncology, Inc.360 enrolled214 locationsNCT07128199
Recruiting
Phase 2

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

Breast CancerEsophageal CancerGastric Cancer+11 more
Daiichi Sankyo740 enrolled84 locationsNCT06172478
Recruiting
Not Applicable

Implementation of Indocyanine Green to Identify Sentinel Lymph Nodes During Surgery for Breast Cancer

Breast CancerSentinel Lymph Node Biopsy (SLNB)Sentinel Lymph Node Detection+6 more
Isabelle Henskens1,760 enrolled7 locationsNCT07146295
Recruiting
Not Applicable

The TASTY-steering Study

Metastatic Triple Negative Breast Cancer or Metastatic Testicular Cancer, or Stage II-IV Diffuse Large B Cell Lymphoma
University Medical Center Groningen201 enrolled11 locationsNCT07258563
Recruiting
Not Applicable

OligoCare TwiCs (Trials Within Cohorts) Trial Comparing Acute Toxicity in Single-fraction vs Multiple-fraction SBRT for Metastasis-directed Treatment (SPRINT)

Breast CancerProstate CancerNSCLC
European Organisation for Research and Treatment of Cancer - EORTC302 enrolled15 locationsNCT06462963
Recruiting
Not Applicable

Minimal Invasive Breast Cancer Excision Using Vacuum Assisted Biopsy Under Ultrasound Guidance

Breast Cancer
Radboud University Medical Center170 enrolled1 locationNCT04107636
Recruiting

OPTImaL:Optimisation of Treatment for Patients With Low Stage Triple-negative Breast Cancer With High Stromal Tumor-infiltrating Lymphocytes

Breast Cancer Stage I
The Netherlands Cancer Institute490 enrolled28 locationsNCT06476119
Recruiting

Cardiopulmonary Toxicity of Thoracic Radiotherapy

Oesophageal Cancer
University Medical Center Groningen320 enrolled3 locationsNCT03978377
Recruiting
Phase 1Phase 2

Study of DF1001 in Patients with Advanced Solid Tumors

Solid Tumor, Adult
Dragonfly Therapeutics378 enrolled52 locationsNCT04143711
Recruiting
Not Applicable

The Beneficial Value of PET/CT in the Follow-up of Stage III Non-small Cell Lung Cancer Patients

Stage III Non-small Cell Lung Cancer
Radboud University Medical Center690 enrolled27 locationsNCT06082492
Recruiting
Not Applicable

Single-dose Preoperative Partial Breast Irradiation in Low-risk Breast Cancer Patients

Breast Cancer
Amsterdam UMC, location VUmc100 enrolled7 locationsNCT05350722