Phase 2 Brain Cancer Clinical Trials

11 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 111 of 11 trials

Recruiting
Phase 2

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

Central Nervous System DiseasesBrain CancerGlioblastoma Multiforme (GBM)+4 more
Black Diamond Therapeutics, Inc.162 enrolled1 locationNCT07326566
Recruiting
Phase 2

Trastuzumab Deruxtecan (T-DXd) for People With Brain Cancer

Metastatic CancerLeptomeningeal MetastasisBrain Cancer+2 more
Memorial Sloan Kettering Cancer Center30 enrolled1 locationNCT06058988
Recruiting
Phase 2

Ruxolitinib With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma

Brain CancerGlioblastomaGlioblastoma Multiforme+4 more
Baptist Health South Florida190 enrolled1 locationNCT06991101
Recruiting
Phase 2

Characterization of 18F-Fluciclovine PET Amino Acid Radiotracer in Resected Brain Metastasis

Brain MetastasesBrain Cancer
Baptist Health South Florida20 enrolled1 locationNCT05554302
Recruiting
Phase 2

Diagnostic Performance of Fluorescein as an Intraoperative Brain Tumor Biomarker

Brain Cancer
David W. Roberts30 enrolled1 locationNCT02691923
Recruiting
Phase 2

Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory GBM, AA, and AOA

Brain TumorBrain CancerGlioblastoma+6 more
Northwell Health37 enrolled1 locationNCT02800486
Recruiting
Phase 1Phase 2

Oral Capecitabine and Temozolomide (CAPTEM) for Newly Diagnosed GBM

CancerBrain TumorBrain Cancer+6 more
Northwell Health67 enrolled1 locationNCT03213002
Recruiting
Phase 1Phase 2

Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma

Brain TumorBrain CancerGlioblastoma+4 more
Northwell Health33 enrolled1 locationNCT02861898
Recruiting
Phase 1Phase 2

TIL Therapy Combined With Pembrolizumab for Advanced Brain Cancer Including Gliomas and Meningiomas

Brain MetastasesBrain TumorBrain Cancer+4 more
Essen Biotech85 enrolled1 locationNCT06640582
Recruiting
Phase 2

Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases

Breast CancerLung CancerMelanoma+3 more
Dana-Farber Cancer Institute134 enrolled2 locationsNCT04899908
Recruiting
Phase 2

SGM-101 in Colorectal Brain Metastases.

Colorectal NeoplasmsGastrointestinal CancerBrain Metastases+10 more
Leiden University Medical Center10 enrolled2 locationsNCT04755920