Phase 1 Brain Metastases Clinical Trials
7 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–7 of 7 trials
Recruiting
Phase 1Phase 2
Delayed or Upfront Brain RAdiotherapy in Treatment naïve Lung Cancer Patients With Asymptomatic or Minimally Symptomatic Brain Metastases and ALK rEarrangements
Lung CancerNSCLCBrain Metastases
Joshua Palmer56 enrolled3 locationsNCT05987644
Recruiting
Phase 1
Fluorine-18-AlphaVBeta6-Binding Peptide Positron Emission Tomography in Metastatic Non-Small Cell Lung Cancer
Lung CancerBrain MetastasesLung Cancer Metastatic
University of California, Davis20 enrolled1 locationNCT05452005
Recruiting
Phase 1Phase 2
Stereotactic Radiation & Abemaciclib in the Management of HR+/HER2- Breast Cancer Brain Metastases
Brain MetastasesHR+ Metastatic Breast Cancer
H. Lee Moffitt Cancer Center and Research Institute31 enrolled2 locationsNCT04923542
Recruiting
Phase 1Phase 2
Defactinib and Avutometinib, With or Without Encorafenib, for the Treatment of Patients With Brain Metastases From Cutaneous Melanoma
Cutaneous MelanomaBrain Metastases
University of Utah33 enrolled2 locationsNCT06194929
Recruiting
Phase 1
Personalized Radiotherapy for Individualized Treatment Strategies and Monitoring (PRISM)
Solid Tumor, AdultBrain MetastasesSmall Cell Lung Cancer Extensive Stage
University of Texas Southwestern Medical Center45 enrolled1 locationNCT07139990
Recruiting
Phase 1Phase 2
Pembrolizumab And Stereotactic Radiosurgery (Srs) Of Selected Brain Metastases In Breast Cancer Patients
Metastatic Breast CancerBrain Metastases
Weill Medical College of Cornell University41 enrolled3 locationsNCT03449238
Recruiting
Phase 1Phase 2
WBRT With Hippocampal-avoidance Technique Followed by SRT for Extensive-stage SCLC With Baseline Brain Metastases
Brain MetastasesSCLC,Extensive Stage
Fudan University56 enrolled1 locationNCT06243003