Phase 2 Breast Cancer Metastatic Clinical Trials

13 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 113 of 13 trials

Recruiting
Phase 2

Trial of Trastuzumab Deruxtecan in Previously Treated HER2

Breast Cancer Metastatic
Yale University40 enrolled2 locationsNCT06750484
Recruiting
Phase 1Phase 2

Target-specific immunoPET Imaging of Breast Cancer

Breast CancerBreast Cancer MetastaticBreast Neoplasms
RenJi Hospital200 enrolled1 locationNCT06715826
Recruiting
Phase 1Phase 2

A Phase 1b/2 Study of the Safety and Efficacy of the Monoclonal Antibody OM-RCA-01 in Patients With Metastatic Tumors Expressing Fibroblast Growth Factor Receptor 1

Breast Cancer MetastaticRenal Cell Carcinoma MetastaticProstate Cancer Metastatic+2 more
Kidney Cancer Research Bureau58 enrolled5 locationsNCT07292168
Recruiting
Phase 1Phase 2

Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer

Breast CancerBreast Cancer MetastaticOvarian Cancer+6 more
Incyclix Bio150 enrolled17 locationsNCT05735080
Recruiting
Phase 2

Prevention of Sacituzumab Govitecan-related Neutropenia in Patients With Metastatic Triple Negative Breast Cancer

Breast Cancer Metastatic
Yeon Hee Park40 enrolled1 locationNCT06616987
Recruiting
Phase 2

The SAPPHO Study: Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer

Breast CancerBreast Cancer MetastaticBreast Cancer Female+3 more
Dana-Farber Cancer Institute72 enrolled1 locationNCT06439693
Recruiting
Phase 1Phase 2

Study of SHR-A1811 Combined With Pyrotinib and Bevacizumab in Advanced Breast Cancer With Brain Metastasis

Breast Cancer MetastaticBreast Cancer Brain Metastases
Fudan University74 enrolled1 locationNCT06718933
Recruiting
Phase 1Phase 2

HER2-PET Imaging in HER2-low Breast Cancers

Breast Cancer Metastatic
Centre de recherche du Centre hospitalier universitaire de Sherbrooke40 enrolled1 locationNCT06732336
Recruiting
Phase 1Phase 2

TIL Gean Therapy Combined With Immunotherapy for Advanced or Metastatic Refractory Breast Cancer

Breast CancerBreast Cancer MetastaticBreast Carcinoma+1 more
Essen Biotech85 enrolled1 locationNCT06532812
Recruiting
Phase 2

A Study to Evaluate the Efficacy and Safety of TSL-1502 Capsules in Breast Cancer Patients With Germline BRCA Mutations

Breast Cancer Metastatic
Jiangsu Tasly Diyi Pharmaceutical Co., Ltd.125 enrolled1 locationNCT05420779
Recruiting
Phase 1Phase 2

Dose-Expansion Modular Study To Explore the Safety, Tolerability, and Anti-tumor Activity of HER3- DXd Monotherapy and Combinations in Patients With Inoperable Advanced Breast Cancer (ABC) After Progression on T-DXd

Breast Cancer MetastaticAdvanced Breast CancerHER2-positive Metastatic Breast Cancer+1 more
Gustave Roussy, Cancer Campus, Grand Paris152 enrolled1 locationNCT06298084
Recruiting
Phase 2

PARP Inhibitor With CDK4/6 Inhibitor and Endocrine Therapy in HR+/ HER2-Advanced Breast Cancer

Breast Cancer Metastatic
Fudan University200 enrolled1 locationNCT05759546
Recruiting
Phase 2

Apatinib With CDK4/6 Inhibitor and Endocrine Therapy in HR+/ HER2- Advanced Breast Cancer

Breast Cancer Metastatic
Fudan University145 enrolled1 locationNCT05759572