Phase 1 Breast Neoplasms Clinical Trials

13 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 113 of 13 trials

Recruiting
Phase 1

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

Breast NeoplasmsColorectal NeoplasmsProstate Neoplasm+2 more
Eli Lilly and Company421 enrolled25 locationsNCT07114601
Recruiting
Phase 1Phase 2

A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer

Breast CancerBreast Neoplasms
Pfizer100 enrolled159 locationsNCT06966453
Recruiting
Phase 1

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

Breast NeoplasmsCholangiocarcinomaOvarian Neoplasms+4 more
Eli Lilly and Company241 enrolled27 locationsNCT07213791
Recruiting
Phase 1Phase 2

Study of Patritumab Deruxtecan With Other Anticancer Agents in Participants With HER2 Positive Breast Cancer That Has Spread and Cannot Be Surgically Removed (MK-1022-009)

Breast CancerBreast Neoplasms
Merck Sharp & Dohme LLC81 enrolled17 locationsNCT06686394
Recruiting
Phase 1

A Study of Mesothelin-Targeted CAR T-Cell Therapy in People With Esophagogastric Cancer

Breast NeoplasmsEsophageal AdenocarcinomaMesothelin Positive+5 more
Memorial Sloan Kettering Cancer Center18 enrolled7 locationsNCT06623396
Recruiting
Phase 1Phase 2

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

Breast NeoplasmsBreast DiseasesNeoplasms+5 more
Stemline Therapeutics, Inc.73 enrolled86 locationsNCT05386108
Recruiting
Phase 1Phase 2

Target-specific immunoPET Imaging of Breast Cancer

Breast CancerBreast Cancer MetastaticBreast Neoplasms
RenJi Hospital200 enrolled1 locationNCT06715826
Recruiting
Phase 1

Focused Ultrasound and Gemcitabine in Breast Cancer

Breast CancerBreast Neoplasms
Patrick Dillon, MD32 enrolled1 locationNCT04796220
Recruiting
Phase 1

A Study of DM001 in Patients With Advanced Solid Tumors

Breast Neoplasms
Xadcera Biopharmaceutical (Suzhou) Co., Ltd.128 enrolled5 locationsNCT06475937
Recruiting
Phase 1

Phase I Study of Autologous Tumor-Draining Lymph Node-Derived Lymphocytes for Advanced HER2-Negative Breast Cancer

Breast Neoplasms
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University24 enrolled1 locationNCT06121557
Recruiting
Phase 1

Phase I Study of Autologous Tumor-Draining Lymph Node-Derived Lymphocytes as Neoadjuvant Therapy for HER2-Negative Breast Cancer

Breast Neoplasms
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University24 enrolled1 locationNCT06121570
Recruiting
Phase 1Phase 2

Study of Autologous Tumor-Draining Lymph Node-Derived Lymphocytes as Neoadjuvant Therapy for HER2-Negative Breast Cancer

Breast Neoplasms
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University196 enrolled1 locationNCT05981014
Recruiting
Phase 1Phase 2

Study of Autologous Tumor-Draining Lymph Node-Derived Lymphocytes for Advanced HER2-Negative Breast Cancer

Breast Neoplasms
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University170 enrolled1 locationNCT05981001