Phase 1 Crohn Disease Clinical Trials

9 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 19 of 9 trials

Recruiting
Phase 1

Nivolumab in Treating Patients With Autoimmune Disorders and Advanced, Metastatic, or Unresectable Cancer

Malignant Solid NeoplasmHematopoietic and Lymphoid Cell NeoplasmRheumatoid Arthritis+11 more
National Cancer Institute (NCI)300 enrolled52 locationsNCT03816345
Recruiting
Phase 1Phase 2

Stem Cell Transplantation in Crohn's Disease

Crohn Disease
Cedars-Sinai Medical Center15 enrolled1 locationNCT04224558
Recruiting
Phase 1Phase 2

Low Dose IL-2 for the Treatment of Crohn's Disease

Crohn Disease
Boston Children's Hospital30 enrolled3 locationsNCT04263831
Recruiting
Phase 1Phase 2

Dose Escalation of Allogeneic Adipose Derived Stroma/Stem Cells for the Treatment of Crohn's Fistula

Crohn Disease
University Hospital, Toulouse9 enrolled1 locationNCT06636032
Recruiting
Phase 1Phase 2

Pilot and Feasibility Study of 2'-FL as a Dietary Supplement in IBD Patients Receiving Stable Maintenance Anti-TNF Therapy

Inflammatory Bowel DiseasesCrohn DiseaseUlcerative Colitis
Children's Hospital Medical Center, Cincinnati116 enrolled3 locationsNCT03847467
Recruiting
Phase 1Phase 2

Fluorescence Imaging of Risankizumab-800CW in Inflammatory Bowel Disease

Ulcerative Colitis (UC)Crohn Disease (CD)
University Medical Center Groningen18 enrolled1 locationNCT06606808
Recruiting
Phase 1Phase 2

Microbial Restoration in Inflammatory Bowel Diseases

Inflammatory Bowel DiseasesCrohn DiseaseMicrobiome+1 more
St Vincent's Hospital Melbourne120 enrolled1 locationNCT04970446
Recruiting
Phase 1

Quantitative Fluorescence Molecular Imaging of Ustekinumab-800CW to Elucidate the Drug Distribution Throughout Inflamed Tissue in Crohn's Disease and Psoriasis.

Crohn DiseasePsoriasis
University Medical Center Groningen56 enrolled1 locationNCT05725876
Recruiting
Phase 1Phase 2

Fluorescence Imaging of Adalimumab-680LT in Inflammatory Bowel Disease

Crohn DiseaseUlcerative Colitis
University Medical Center Groningen21 enrolled1 locationNCT06117423