Phase 2 Cutaneous Squamous Cell Carcinoma Clinical Trials
17 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–17 of 17 trials
Recruiting
Phase 1Phase 2
Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Metastatic Triple-Negative Breast Carcinoma+97 more
Mayo Clinic132 enrolled1 locationNCT05269381
Recruiting
Phase 2
Pembrolizumab for the Treatment of Locally Advanced and/or Recurrent Orbital or Periocular Cutaneous Squamous Cell Carcinoma
Recurrent Cutaneous Squamous Cell Carcinoma of the Head and NeckLocally Advanced Cutaneous Squamous Cell Carcinoma of the Head and NeckStage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8
University of Michigan Rogel Cancer Center22 enrolled1 locationNCT06580054
Recruiting
Phase 1Phase 2
Study to Investigate the Efficacy and Safety of RP1 in Adult Patients With Organ Transplants and Advanced Skin Malignancies
CancerMerkel Cell CarcinomaBasal Cell Carcinoma+1 more
Replimune Inc.90 enrolled28 locationsNCT04349436
Recruiting
Phase 2
Intensity Modulated Proton or X-Ray Therapy After Surgery for Treatment of Head and Neck Cancer, the HEADLIGHT Study
Head and Neck CarcinomaSalivary Gland CarcinomaMetastatic Malignant Neoplasm in the Lymph Nodes+9 more
Mayo Clinic174 enrolled9 locationsNCT05075980
Recruiting
Phase 2
TIL Therapy in cSCC and MCC
Merkel Cell CarcinomaCutaneous Squamous Cell CarcinomaSkin Cancer+1 more
Karam Khaddour, MD, MS14 enrolled1 locationNCT07288073
Recruiting
Phase 2
Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer
Head and Neck Squamous Cell CarcinomaStage III Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8+38 more
NRG Oncology98 enrolled143 locationsNCT06532279
Recruiting
Phase 2
Phase 2 Study of Ivonescimab in Patients With Cutaneous Squamous Cell Carcinoma
Cutaneous Squamous Cell Carcinoma
M.D. Anderson Cancer Center24 enrolled1 locationNCT06567314
Recruiting
Phase 2
Neoadjuvant Nivolumab and Relatlimab in Cutaneous Squamous Cell Carcinoma
Cutaneous Squamous Cell Carcinoma
Melanoma Institute Australia20 enrolled1 locationNCT06288191
Recruiting
Phase 2
Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program
Urothelial CarcinomaEsophageal CarcinomaHepatocellular Carcinoma+28 more
Mayo Clinic50 enrolled1 locationNCT06265285
Recruiting
Phase 2
Ivonescimab Before Surgery for the Treatment of Resectable Stage II-IV Head and Neck Cancer
Advanced Head and Neck Squamous Cell CarcinomaResectable Head and Neck Squamous Cell CarcinomaStage II Head and Neck Cutaneous Squamous Cell Carcinoma+2 more
University of Michigan Rogel Cancer Center28 enrolled1 locationNCT07094685
Recruiting
Phase 2
Phase 2 Pragmatic Trial of Sentinel Lymph Node Biopsy (SLNB) in Patients With Clinically Node-Negative (cN0), High-Risk Cutaneous Squamous Cell Carcinoma (cSCC) of the Head and Neck
Cutaneous Squamous Cell Carcinoma of the Head and NeckClinically Node-Negative (cN0)High-Risk Cutaneous Squamous Cell Carcinoma (cSCC) of the Head and Neck
University of California, Davis24 enrolled1 locationNCT06990737
Recruiting
Phase 1Phase 2
A Beta-only IL-2 ImmunoTherapY Study
Triple-Negative Breast CancerEsophageal CancerGastric Cancer+34 more
Medicenna Therapeutics, Inc.115 enrolled27 locationsNCT05086692
Recruiting
Phase 1Phase 2
Study of an Anti-HER3 Antibody, HMBD-001, With Docetaxel +/- Cetuximab in Advanced Squamous Non-small Cell Lung Cancers, and HMBD-001 + Cetuximab in Advanced Squamous Cell Cancers
Advanced or Metastatic Squamous Non-Small Cell Lung CancerAdvanced Head and Neck Squamous Cell CarcinomaAdvanced Esophageal Squamous Cell Carcinoma+2 more
Hummingbird Bioscience98 enrolled20 locationsNCT05910827
Recruiting
Phase 2
Towards Cure Via Only Ultra-short ICB in CSCC
Cutaneous Squamous Cell CancerCutaneous Squamous Cell CarcinomaCutaneous Squamous Cell Carcinoma (CSCC)+1 more
The Netherlands Cancer Institute41 enrolled5 locationsNCT06823479
Recruiting
Phase 1Phase 2
Microneedle Array Plus Doxorubicin in Cutaneous Squamous Cell Cancer (cSCC)
Cutaneous Squamous Cell CarcinomaSkin Cancers - Squamous Cell Carcinoma
Falo, Louis, MD48 enrolled1 locationNCT05377905
Recruiting
Phase 2
Evaluating the Use of Photodynamic Therapy to Treat Facial Cutaneous Squamous Cell Carcinoma in Situ (SCCis)
Cutaneous Squamous Cell Carcinoma
The Center for Clinical and Cosmetic Research20 enrolled1 locationNCT06577311
Recruiting
Phase 2
Neoadjuvant Pembrolizumab in Cutaneous Squamous Cell Carcinoma
Head and Neck CancerCutaneous Squamous Cell Carcinoma of the Head and Neck
Queensland Health27 enrolled3 locationsNCT05025813