Phase 2 Gastroesophageal-junction Cancer Clinical Trials
11 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–11 of 11 trials
Recruiting
Phase 1Phase 2
Study for AZD4360 in Participants With Advanced Solid Tumours
Gastric CancerGastroesophageal-junction CancerBiliary Tract Cancer+1 more
AstraZeneca117 enrolled17 locationsNCT06921928
Recruiting
Phase 1Phase 2
EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors
Endometrial CancerAdvanced Solid TumorsMSI-H or dMMR Advanced Solid Tumors+4 more
Eikon Therapeutics160 enrolled10 locationsNCT07262619
Recruiting
Phase 2
AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2
Gastric CancerGastroesophageal-junction CancerBiliary Tract Cancer+1 more
AstraZeneca224 enrolled52 locationsNCT06219941
Recruiting
Phase 2
A Trial of Adebrelimab Plus (SHR-A1811/SHR-A1904 With Chemotherapy) or SHR-8068 as Treatment for Gastric/GEJ Cancer
Gastric CancerGastroesophageal-junction Cancer
Suzhou Suncadia Biopharmaceuticals Co., Ltd.200 enrolled2 locationsNCT07110571
Recruiting
Phase 2
Iparomlimab and Tuvonralimab (QL1706) Combined With Chemotherapy for Previously Untreated Advanced or Metastatic Gastric or Gastroesophageal Junction Cancer
Gastroesophageal-junction CancerMetastatic Gastric CancerAdvanced Gastric Cancer+1 more
Beijing Friendship Hospital32 enrolled1 locationNCT07315854
Recruiting
Phase 2
Zimberelimab Anti-PD1 +/- Domvanalimab in Resectable Mmrd Gastric Cancer
Locally Advanced Gastric AdenocarcinomaMSI-H/dMMR Gastric CancerMSI-H/dMMR Gastroesophageal-junction Cancer
Royal Marsden NHS Foundation Trust50 enrolled9 locationsNCT06250036
Recruiting
Phase 1Phase 2
A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors
Colorectal, CancerEsophageal CancerGastric Cancer+5 more
Merus B.V.523 enrolled45 locationsNCT03526835
Recruiting
Phase 2
Radiotherapy + Chemoimmunotherapy Followed by Surgery in Patients With Limited Metastatic Gastric or GEJ Cancer
Gastroesophageal-junction CancerGastroesophageal Junction AdenocarcinomaMetastatic Cancer+6 more
Fudan University55 enrolled1 locationNCT06121700
Recruiting
Phase 2
XELOX Combined With Anlotinib and Penpulimab vs XELOX as Adjuvant Therapy in ctDNA Positive Gastric and Esophagogastric Junction Adenocarcinoma
Gastric CancerGastroesophageal-junction CancerCarcinoma+4 more
The First Affiliated Hospital with Nanjing Medical University80 enrolled1 locationNCT05494060
Recruiting
Phase 2
Tislelizumab in Combination With Pre-operative CRT Versus SOC for Locally Advanced G/GEJ Adenocarcinoma
Gastric CancerGastroesophageal-junction Cancer
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School140 enrolled3 locationsNCT05687357
Recruiting
Phase 1Phase 2
Tepotinib Plus Paclitaxel in MET Amplified or MET Exon 14 Alterated Gastric and GEJ Carcinoma
Gastric CancerGastroesophageal-junction Cancer
Hallym University Medical Center42 enrolled1 locationNCT05439993