Phase 3 Glioblastoma Clinical Trials

14 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 114 of 14 trials

Recruiting
Phase 3

Treatment Intensification With Temozolomide in Adults With a Glioblastoma

Glioblastoma
Centre Oscar Lambret486 enrolled19 locationsNCT03663725
Recruiting
Phase 3

Study of TLX101-Tx Plus Standard of Care (SoC) Versus SoC Alone for the Treatment of Patients With Recurrent Glioblastoma

GlioblastomaNeoplastic DiseaseGlioblastoma (GBM)+3 more
Telix Pharmaceuticals (Innovations) Pty Limited50 enrolled4 locationsNCT07100730
Recruiting
Phase 3

EF-41/KEYNOTE D58: Phase 3 Study of Optune Concomitant With Temozolomide Plus Pembrolizumab in Newly Diagnosed Glioblastoma

Glioblastoma
NovoCure GmbH741 enrolled82 locationsNCT06556563
Recruiting
Phase 3

Advanced Imaging Techniques for Evaluating the Tumor Immune Microenvironment in Glioblastoma Patients

Glioblastoma
Jonsson Comprehensive Cancer Center15 enrolled1 locationNCT07461948
Recruiting
Phase 3

Beginning Radiation Immediately With GammaTile at GBM Excision Versus Standard of Care

Glioblastoma
GT Medical Technologies, Inc.766 enrolled3 locationsNCT07195591
Recruiting
Phase 3

Lomustine With and Without Reirradiation for First Progression of Glioblastoma: a Randomized Phase III Study

First Progression of Glioblastoma
European Organisation for Research and Treatment of Cancer - EORTC411 enrolled43 locationsNCT05904119
Recruiting
Phase 3

A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

Brain TumorGlioblastomaGBM+1 more
Ivy Brain Tumor Center450 enrolled93 locationsNCT06388733
Recruiting
Phase 2Phase 3

Antisecretory Factor Glioblastoma Phase 2

Glioblastoma
Peter Siesjö300 enrolled1 locationNCT05669820
Recruiting
Phase 2Phase 3

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

Glioblastoma
Global Coalition for Adaptive Research1,280 enrolled62 locationsNCT03970447
Recruiting
Phase 3

Anterior Temporal Lobectomy in Temporal Glioblastoma

Newly Diagnosed GlioblastomaTemporal Lobe
University Hospital, Bonn178 enrolled1 locationNCT07021339
Recruiting
Phase 3

Conventional Versus Hypofractionated Radiotherapy With Temozolomide in Elderly Glioblastoma

Glioblastoma
Severance Hospital178 enrolled1 locationNCT05439278
Recruiting
Phase 3

A Prospective Pivotal Study to Evaluate the Efficacy and Safety of Avastin® Bevacizumab (BEV) With or Without Microbubble-mediated Focused Ultrasound (FUS-MB) Using NaviFUS System in Recurrent Glioblastoma Multiforme Patients

NeoplasmsBrain TumorGlioblastoma+5 more
NaviFUS Corporation32 enrolled2 locationsNCT06496971
Recruiting
Phase 3

Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM

Brain CancerGlioblastomaGBM+4 more
Northwell Health432 enrolled1 locationNCT05271240
Recruiting
Phase 2Phase 3

Dendritic Cell Immunotherapy Against Cancer Stem Cells in Glioblastoma Patients Receiving Standard Therapy

Glioblastoma
Oslo University Hospital60 enrolled1 locationNCT03548571