Phase 2 HIV Clinical Trials

57 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 57 trials

Recruiting
Phase 2

Therapy Adapted for High Risk and Low Risk HIV-Associated Anal Cancer

HIV InfectionAnal Squamous Cell CarcinomaStage II Rectal Cancer AJCC v8+7 more
National Cancer Institute (NCI)40 enrolled14 locationsNCT04929028
Recruiting
Phase 2

Imaging and Biopsy of People With HIV-1 Undergoing Analytic Treatment Interruption

HIV
National Cancer Institute (NCI)50 enrolled1 locationNCT05419024
Recruiting
Phase 2

A Phase 2b Study Evaluating Oral VH4524184 Regimens in Treatment Naïve Persons With HIV-1 (INNOVATE Study)

HIV Infections
ViiV Healthcare150 enrolled62 locationsNCT07202546
Recruiting
Phase 2

Evaluating the Safety and Immunogenicity of MTBVAC

TuberculosisHIV I Infection
HIV Vaccine Trials Network276 enrolled16 locationsNCT05947890
Recruiting
Phase 2

COVID-19 Booster and IIV Schedule in Immunocompromised Hosts

COVID-19Inflammatory Bowel DiseaseRheumatoid Arthritis (RA)+5 more
McGill University Health Centre/Research Institute of the McGill University Health Centre660 enrolled3 locationsNCT06599658
Recruiting
Phase 1Phase 2

Trial of Allogeneic Reduced-Intensity, HLA-Haploidentical Allogeneic Hematopoietic Cell Bone Marrow Transplantation Followed by Graft-versus-Host-Disease (GVHD) Prophylaxis With Cyclophosphamide, Bortezomib and Maraviroc for Hematologic Malignancies ...

Hematologic MalignanciesHIV
National Cancer Institute (NCI)265 enrolled1 locationNCT05470491
Recruiting
Phase 1Phase 2

Exploratory Study of LP-98 for Injection in ART-Naive HIV-Infected Individuals

HIV
Shanxi Kangbao Biological Product Co., Ltd.30 enrolled1 locationNCT07433387
Recruiting
Phase 2

Improving Physical Ability and Cellular Senescence Elimination in HIV

FrailtyHIVAging Problems+1 more
National Institute of Allergy and Infectious Diseases (NIAID)80 enrolled27 locationsNCT07144293
Recruiting
Phase 2

Doravirine (DOR) in Human Immunodeficiency Virus (HIV)-Infected Children Aged 4 Weeks to <12 Years and <45 kg (MK-1439-066)

Human Immunodeficiency Virus (HIV) Infection
Merck Sharp & Dohme LLC84 enrolled24 locationsNCT04375800
Recruiting
Phase 2Phase 3

A Clinical Study of Islatravir and Ulonivirine for People With HIV-1 Who Have Not Been Treated Before (MK-8591B-062)

Human Immunodeficiency Virus Type 1 (HIV-1) Infection
Merck Sharp & Dohme LLC570 enrolled24 locationsNCT07266831
Recruiting
Phase 1Phase 2

Effects of Vagal Dysfunction on Gastrointestinal and Inflammatory Pathways in HIV

HIVNon-HIVVagus Nerve Dysfunction
Icahn School of Medicine at Mount Sinai207 enrolled1 locationNCT04353778
Recruiting
Phase 2

HIV-1 Virologic Suppression With TMB-365 and TMB-380 Antibodies Study

HIV-1-infection
TaiMed Biologics Inc.75 enrolled11 locationsNCT07215468
Recruiting
Phase 2

An Integrated Intervention Using a Pill Ingestible Sensor System

Medication AdherenceSocial Determinants of Health (SDOH)HIV/AIDS
University of California, Los Angeles110 enrolled1 locationNCT06480578
Recruiting
Phase 1Phase 2

Evaluation of Safety, Immunogenicity and Efficacy of a Triple Immune Regimen in Adults Initiated on ART During Acute HIV-1

HIV-1-infection
National Institute of Allergy and Infectious Diseases (NIAID)36 enrolled12 locationsNCT06071767
Recruiting
Phase 2

Combination Vaccination and Broadly Neutralising Antibody Therapy in HIV

HIV
University of Oxford48 enrolled3 locationsNCT07054931
Recruiting
Phase 2

Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 1

Alcohol Use DisorderHIV
Yale University30 enrolled1 locationNCT06004830
Recruiting
Phase 2

Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 3 Semaglutide

HIVAlcohol Use Disorder (AUD)
Yale University30 enrolled1 locationNCT07040592
Recruiting
Phase 2

A Phase Ⅱa Clinical Study of CL-197 Capsules

HIV-1-infection
Henan Genuine Biotech Co., Ltd.24 enrolled1 locationNCT07308782
Recruiting
Phase 2Phase 3

Platform Trial For Cryptococcal Meningitis

HIVCryptococcal Meningitis
University of Minnesota2,000 enrolled2 locationsNCT06666322
Recruiting
Phase 2

Effect of Empagliflozin on Metabolic Outcomes in Adults Living With HIV Receiving Dolutegravir-Based Therapy

Metabolic SyndromeObesity, OverweightHIV (Human Immunodeficiency Virus)
Abdelrahman Mahmoud66 enrolled1 locationNCT07336797