Kidney Cancer Clinical Trials

69 recruiting

Frequently Asked Questions

Common questions about Kidney Cancer clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 69 trials

Recruiting

Collection of Serum and Tissue Samples From Patients With Biopsy-Proved or Suspected Malignant Disease

Bladder CancerKidney CancerRenal Cancer+2 more
National Cancer Institute (NCI)5,950 enrolled1 locationNCT00026884
Recruiting

Von Hippel-Lindau (VHL): Clinical Manifestations, Diagnosis, Management and Molecular Bases of Inherited Renal and Other Urologic Malignant Disorders

Renal Cell CarcinomaKidney CancerClear Cell Renal Cancer+2 more
National Cancer Institute (NCI)5,000 enrolled1 locationNCT00001238
Recruiting
Phase 2

Comprehensive Multimodal Prehabilitation Alone or With Neoadjuvant Therapy Before Major Cancer Surgery

Bladder CancerKidney CancersOvarian Cancer (OvCa)+1 more
The Methodist Hospital Research Institute148 enrolled1 locationNCT07050771
Recruiting
Phase 1

Open-Label Phase 1/2 Study of NEO-811 in Subjects With Locally Advanced or Metastatic Non-Resectable Clear Cell Renal Cell Carcinoma

Renal Cell CarcinomaClear Cell Renal Cell CarcinomaKidney Cancers+6 more
Neomorph, Inc30 enrolled7 locationsNCT07300241
Recruiting

Hereditary Leiomyomatosis Renal Cell Cancer - Study of the Genetic Cause and the Predisposition to Renal Cancer

Kidney CancerRenal Tumor HistologyCutaneous Leiomyoma
National Cancer Institute (NCI)1,130 enrolled1 locationNCT00050752
Recruiting

Genetic Analysis of Birt Hogg-Dube Syndrome and Characterization of Predisposition to Kidney Cancer

Kidney CancerKidney NeoplasmsPneumothorax+1 more
National Cancer Institute (NCI)950 enrolled1 locationNCT00033137
Recruiting
Phase 1Phase 2

EBNK-001 Allogeneic NK Cells With Low-Dose IL-15 ± Pembrolizumab in Advanced Solid Tumors

Colorectal, CancerEsophageal CancerOvarian Cancer+12 more
Essen Biotech83 enrolled1 locationNCT07410676
Recruiting

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

Colorectal, CancerPancreatic CancerHead and Neck Squamous Cell Carcinoma (HNSCC)+14 more
A2 Biotherapeutics Inc.200 enrolled16 locationsNCT04981119
Recruiting
Not Applicable

An Investigation of Kidney and Urothelial Tumor Metabolism in Patients Undergoing Surgical Resection and/or Biopsy

Urothelial CarcinomaMetastatic Urothelial CarcinomaRenal Cell Carcinoma+9 more
University of Texas Southwestern Medical Center600 enrolled1 locationNCT04623502
Recruiting

Integrated Cancer Repository for Cancer Research

Breast CancerLiver CancerEsophageal Cancer+47 more
University of Nebraska999,999 enrolled45 locationsNCT02012699
Recruiting
Phase 3

Systemic Therapy Alone or With Stereotactic Body Radiotherapy for Oligometastatic Kidney Cancer (STROKER Study)

Renal Cell Carcinoma MetastaticRenal Cell Carcinoma (Kidney Cancer)Kidney Cancer Metastatic
Sun Yat-sen University252 enrolled9 locationsNCT06726421
Recruiting

Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies

Liver CancerColorectal, CancerEndometrial Cancer+12 more
Elephas2,000 enrolled8 locationsNCT07327489
Recruiting
Phase 1

KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

Non-small Cell Lung Cancer (NSCLC)Pancreatic Ductal Adenocarcinoma (PDAC)Colorectal Cancer (CRC)+4 more
Kura Oncology, Inc.300 enrolled32 locationsNCT06026410
Recruiting

Observational Basket Trial to Collect Tissue to Develop and Train a Live Tumor Diagnostic Platform

Liver CancerColorectal, CancerEndometrial Cancer+16 more
Elephas416 enrolled12 locationsNCT05520099
Recruiting
Not Applicable

Targeted Abdominal CT in Conjunction With Lung Cancer Screening

Renal Cell Carcinoma (Kidney Cancer)Kidney CancersAAA - Abdominal Aortic Aneurysm+1 more
University of Cambridge6,272 enrolled1 locationNCT07171190
Recruiting
Not Applicable

Patient Navigation Program to Improve Clinical Trial Enrollment in Cancer Patients

Prostate CancerKidney Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins90 enrolled2 locationsNCT06138067
Recruiting
Not Applicable

Designing Visual Tools to Enhance Cancer Surgeon Decision-making

Prostate CancerKidney Cancer
UNC Lineberger Comprehensive Cancer Center220 enrolled2 locationsNCT06965192
Recruiting

Renal Cancer Monitoring Based on ctDNA Methylomics: A Prospective Cohort Study (MEMORY Study)

Renal Cell CarcinomaCarcinomaKidney Cancer+2 more
Jinling Hospital, China450 enrolled1 locationNCT05917106
Recruiting

Liquid Biopsy Evaluation and Repository Development at Princess Margaret

Breast CancerOvarian CancerLung Cancer+15 more
University Health Network, Toronto2,500 enrolled1 locationNCT03702309
Recruiting
Phase 1

[212Pb]VMT-Alpha-NET in Metastatic or Inoperable Somatostatin-Receptor Positive Gastrointestinal Neuroendocrine Tumors, Pheochromocytoma/Paragangliomas, Small Cell Lung, Renal Cell, and Head and Neck Cancers

Kidney CancersHead and Neck TumorsSmall Cell Lung Cancers+3 more
National Cancer Institute (NCI)120 enrolled1 locationNCT06479811