Early Phase 1 Multiple Myeloma Clinical Trials

26 recruitingEarly Phase 1

What is a Early Phase 1 trial?

Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.

Showing 120 of 26 trials

Recruiting
Early Phase 1

Pilot Study Dara-CyBorD in Newly Diagnosed Multiple Myeloma Patients With Renal Failure

Multiple MyelomaRenal Failure
Augusta University30 enrolled1 locationNCT06142396
Recruiting
Early Phase 1

In-Human CXCR4 Imaging of Hematologic and Solid Tumors Using [68Ga]-Pentixafor-PET

Non-Hodgkin LymphomaMultiple MyelomaErdheim-Chester Disease+2 more
Memorial Sloan Kettering Cancer Center30 enrolled1 locationNCT05093335
Recruiting
Early Phase 1

Universal CAR-T Cells (REVO-UWD-00B) for Refractory and Relapsed Multiple Myeloma

Multiple MyleomaRefractory and Relapsed Multiple Myeloma
Wondercel Biotech (ShenZhen)30 enrolled1 locationNCT06663046
Recruiting
Early Phase 1

JY232(JY232) Injection in Relapsed/Refractory Multiple Myeloma

Multiple Myeloma
Shenzhen Genocury Biotech Co., Ltd.9 enrolled1 locationNCT07336823
Recruiting
Early Phase 1

PET Imaging Study of 68Ga-NB381 in Multiple Myeloma

Multiple Myeloma
Peking University First Hospital30 enrolled1 locationNCT06385652
Recruiting
Early Phase 1

A Clinical Study to Evaluate LVIVO-TaVec200 for the Treatment of Relapsed/Refractory Multiple Myeloma

Multiple Myeloma
The First Affiliated Hospital with Nanjing Medical University36 enrolled5 locationsNCT07294625
Recruiting
Early Phase 1

CAR19-BCMA Dual-target CAR-T in the Treatment of Relapsed / Refractory Multiple Myeloma

Multiple Myeloma
Institute of Hematology & Blood Diseases Hospital, China9 enrolled1 locationNCT07249073
Recruiting
Early Phase 1

A Study of CT0596 in Relapsed/Refractory Multiple Myeloma and Relapsed/ Refractory Plasma Cell Leukemia

Relapsed/Refractory Multiple MyelomaRelapsed/Refractory Plasma Cell Leukemia
The First Affiliated Hospital of Soochow University24 enrolled1 locationNCT06730256
Recruiting
Early Phase 1

Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies

Chronic Myeloid LeukemiaHodgkin LymphomaNon-Hodgkin Lymphoma+9 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins8 enrolled1 locationNCT06398457
Recruiting
Early Phase 1

An Open-label, Single-arm Clinical Study to Evaluate the Safety and Preliminary Efficacy of OriV508 Injection in Treating Relapsed/Refractory Hematological Malignancies

Non-Hodgkin Lymphoma (NHL)Multiple Myeloma (MM)
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology40 enrolled1 locationNCT07101705
Recruiting
Early Phase 1

64Cu-LLP2A for Imaging Hematologic Malignancies

Chronic Lymphocytic LeukemiaMultiple MyelomaFollicular Lymphoma+4 more
Washington University School of Medicine42 enrolled1 locationNCT06636175
Recruiting
Early Phase 1

Safety and Efficacy of Metabolically Armed BCMA CAR-T Cells (Meta10-BCMA) in the Treatment of r/r Plasma Cell Neoplasms Clinical Research

Multiple Myeloma (MM)Plasma Cell Leukemia (PCL)AL Amyloidosis (AL)
Anhui Provincial Hospital36 enrolled1 locationNCT07085559
Recruiting
Early Phase 1

A Clinical Study of Allogeneic CD19/BCMA CAR-T Cells for the Treatment of R/R B-cell Malignant Tumors

Multiple MyelomaB-cell Lymphoma
YANRU WANG21 enrolled1 locationNCT06976437
Recruiting
Early Phase 1

A Molecular Probe Targeting BCMA for the Clinical Diagnosis of Multiple Myeloma

Multiple Myeloma and Malignant Plasma Cell Neoplasms
Peking University First Hospital50 enrolled2 locationsNCT06717113
Recruiting
Early Phase 1

A Study to Evaluate CG-105-12 in Patients With Relapsed/Refractory Multiple Myeloma

Multiple MyelomaRelapsed/Refractory
The First Affiliated Hospital of Nanchang University12 enrolled1 locationNCT06999031
Recruiting
Early Phase 1

VitD3 Supplementation in Patients With Multiple Myeloma

Multiple Myeloma
Amany Keruakous, MD, MS.100 enrolled1 locationNCT05846880
Recruiting
Early Phase 1

A Clinical Study to Evaluate the Safety and Efficacy of ESO-T01 in Treating Relapsed/Refractory Multiple Myeloma.

Multiple Myeloma
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology24 enrolled1 locationNCT06691685
Recruiting
Early Phase 1

A Study of ESO-T01 in Treating Relapsed/ Refractory Multiple Myeloma

Relapsed/Refractory Multiple Myeloma
Chunrui Li24 enrolled1 locationNCT06791681
Recruiting
Early Phase 1

Pilot Study Using Changes in Serum BCMA to Determine Disease Progression in Multiple Myeloma

Multiple Myeloma
Oncotherapeutics30 enrolled1 locationNCT06209606
Recruiting
Early Phase 1

A Dose Escalating Study of CD19/CD22/BCMA CAR-T Therapy in Relapsed/ Refractory Multiple Myeloma

Multiple MyelomaRelapsedRefractory
Shanghai Cell Therapy Group Co.,Ltd12 enrolled1 locationNCT06732232