Phase 2 Muscle-Invasive Bladder Carcinoma Clinical Trials
12 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–12 of 12 trials
Recruiting
Phase 2
Sacituzumab Govitecan Before Radical Cystectomy for the Treatment of Non-Urothelial Muscle Invasive Bladder Cancer
Muscle-Invasive Bladder CarcinomaStage II Bladder Cancer AJCC v8Stage IIIA Bladder Cancer AJCC v8
University of Washington18 enrolled1 locationNCT05581589
Recruiting
Phase 2
Partial Cystectomy & Extended Pelvic Lymph Node Dissection With SOC Perioperative Systemic Therapy
Muscle-Invasive Bladder CarcinomaMalignant Neoplasm of Bladder
Case Comprehensive Cancer Center40 enrolled1 locationNCT06290687
Recruiting
Phase 1Phase 2
Enfortumab Vedotin and Pembrolizumab Combined With Radiotherapy in Muscle Invasive Bladder Cancer
Muscle-Invasive Bladder CarcinomaBladder CancerStage II Bladder Cancer AJCC v8+1 more
University of California, San Francisco47 enrolled1 locationNCT06470282
Recruiting
Phase 2
Bladder Preservation for Patients With Muscle Invasive Bladder Cancer (MIBC) With Variant Histology
Muscle-Invasive Bladder CarcinomaTumor
Leslie Ballas20 enrolled1 locationNCT06417190
Recruiting
Phase 2
Futibatinib in Combination With Durvalumab Prior to Cystectomy for the Treatment of Muscle-Invasive Bladder Cancer Patients Who Are Ineligible for Cisplatin-based Therapy
Muscle-Invasive Bladder CarcinomaStage II Bladder Cancer AJCC v8Stage IIIA Bladder Cancer AJCC v8+1 more
Yuanquan Yang24 enrolled3 locationsNCT06263153
Recruiting
Phase 2
Gemcitabine/Cisplatin Plus Cemiplimab With or Without Fianlimab in Localized Muscle-invasive Bladder Cancer (NeoSTOP-IT)
Muscle-Invasive Bladder CarcinomaBladder Cancer
Columbia University36 enrolled1 locationNCT06571708
Recruiting
Phase 2Phase 3
NEO-BLAST: Neoadjuvant Therapy for Bladder Cancer Followed by Active Surveillance vs Treatment
Muscle-Invasive Bladder Carcinoma
Peter Black688 enrolled1 locationNCT06537154
Recruiting
Phase 2
Surveillance of the Genetic Signature in Circulating Tumor DNA for Guiding Adjuvant Chemotherapy in Urothelial Carcinoma
Muscle-Invasive Bladder CarcinomaMuscle Invasive Bladder Urothelial Carcinoma
Yung NA20 enrolled1 locationNCT06257017
Recruiting
Phase 2Phase 3
Modular Trial of sEphB4-HSA in EphrinB2-High Solid Tumors
Metastatic Urothelial CarcinomaMuscle-Invasive Bladder Carcinoma
Vasgene Therapeutics, Inc700 enrolled1 locationNCT06493552
Recruiting
Phase 2
Evaluating the Impact of 18F-FDG-PET-CT on Risk Stratification and Treatment Adaptation for Patients with Muscle Invasive Bladder Cancer
Muscle-Invasive Bladder Carcinoma
University Hospital, Ghent156 enrolled1 locationNCT04724928
Recruiting
Phase 1Phase 2
RC48 Combined with Toripalimab As Neoadjuvant Therapy for Cisplatin Ineligible MIBC Patients
Muscle-Invasive Bladder CarcinomaBladder Cancer
Zhujiang Hospital55 enrolled1 locationNCT06341400
Recruiting
Phase 2
Cisplatin, Nab-paclitaxel, Nivolumab With Radiotherapy After Resection of Non-Metastatic Muscle Invasive Bladder Cancer
Muscle-Invasive Bladder Carcinoma
Fondazione Policlinico Universitario Agostino Gemelli IRCCS32 enrolled1 locationNCT05203913