Phase 2 Obesity Clinical Trials
31 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 31 trials
Recruiting
Phase 2
A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 Diabetes
ObesityDiabetes Mellitus, Type 2Overweight
Eli Lilly and Company200 enrolled38 locationsNCT07215559
Recruiting
Phase 1Phase 2
Sympathetic Mechanisms in Obesity-Crossover Design
ObesityHypertension
Vanderbilt University Medical Center12 enrolled1 locationNCT05312892
Recruiting
Phase 2
Aleniglipron Phase 2 in Type 2 Diabetes Mellitus
ObesityWeight LossObese+1 more
Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics50 enrolled17 locationsNCT07400588
Recruiting
Phase 1Phase 2
A Study of MET233 in Combination With MET097 in Individuals With Obesity or Overweight With or Without Diabetes
Obesity and Obesity-related Medical Conditions
Metsera, a wholly owned subsidiary of Pfizer132 enrolled1 locationNCT06924320
Recruiting
Phase 2
Metformin IN Asthma for Overweight and Obese Individuals (MINA)
AsthmaOverweight and ObesityAsthma Chronic
Johns Hopkins University100 enrolled2 locationsNCT06273072
Recruiting
Phase 2
TIRzepatide for the Treatment of Obesity in Patients With Atrial Fibrillation
ObesityAtrial Fibrillation
The Cleveland Clinic100 enrolled1 locationNCT06802081
Recruiting
Phase 2
Effect of Empagliflozin on Metabolic Outcomes in Adults Living With HIV Receiving Dolutegravir-Based Therapy
Metabolic SyndromeObesity, OverweightHIV (Human Immunodeficiency Virus)
Abdelrahman Mahmoud66 enrolled1 locationNCT07336797
Recruiting
Phase 2
Study on the Efficacy and Safety of HRS-7535 in Patients With Mild Decrease in Ejection Fraction/Preserved Ejection Fraction Heart Failure and Obesity
Adults With Heart Failure, Mild Decrease in Ejection Fraction/Preserved Ejection Fraction, and Obesity
Shandong Suncadia Medicine Co., Ltd.225 enrolled1 locationNCT06820099
Recruiting
Phase 1Phase 2
Study of ARO-ALK7 in Adult Volunteers With Obesity With and Without Type 2 Diabetes Mellitus
ObesityDiabetes Mellitus, Type 2
Arrowhead Pharmaceuticals126 enrolled8 locationsNCT06937203
Recruiting
Phase 2
Effects of Tirzepatide on Weight Loss and Chronic Inflammation in People With HIV
Obesity and OverweightHIVChronic Inflammation
University of Hawaii12 enrolled1 locationNCT06935838
Recruiting
Phase 2
UBT251 Injection Phase II Clinical Study (CKD)
Chronic Kidney DiseaseObesity &Amp; Overweight
The United Bio-Technology (Hengqin) Co., Ltd.180 enrolled1 locationNCT07134335
Recruiting
Phase 2Phase 3
A Randomised, Controlled Trial of a Low-energy Diet for Improving Functional Status in Heart Failure With PRESERVED Ejection Fraction Preserved Ejection Fraction
Diabetes Mellitus, Type 2Heart Failure With Preserved Ejection FractionHeart Failure, Diastolic+2 more
University of Leicester63 enrolled3 locationsNCT05887271
Recruiting
Phase 2
Food Effect, Efficacy and Safety of MKP10241 in Healthy and Obese Adult Participants, With and Without Diabetes
ObesityType 2 Diabetes Mellitus (T2DM)Food Effect+1 more
Mankind Pharma Limited68 enrolled1 locationNCT07098663
Recruiting
Phase 2Phase 3
GnRHa + Letrozole in Obese Progestin-insensitive Endometrial Cancer Patients
ObesityEndometrial NeoplasmsAtypical Endometrial Hyperplasia+1 more
Xiaojun Chen29 enrolled2 locationsNCT06379113
Recruiting
Phase 2
Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV
FrailtyAgingHIV-1-infection+2 more
Massachusetts General Hospital100 enrolled2 locationsNCT06554717
Recruiting
Phase 2
Efficacy and Safety of Phentermine/Topiramate in Youth With Hypothalamic Obesity
CraniopharyngiomaHypothalamic ObesityHypothalamic Tumor
Seattle Children's Hospital24 enrolled2 locationsNCT06299891
Recruiting
Phase 2
The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action
ObesityType 1 Diabetes
Heba M. Ismail114 enrolled1 locationNCT05414409
Recruiting
Phase 2
A Study of IBI362 in Subjects With HFpEF or HFmrEF Combined With Obesity
ObesityHeart Failure With Preserved Ejection Fraction (HFpEF)Heart Failure With Mildly Reduced Ejection Fraction
Innovent Biologics (Suzhou) Co. Ltd.141 enrolled1 locationNCT06862908
Recruiting
Phase 2
Supplementing L-citrulline to Overweight Late Asthma oNset Phenotypes
ObesityAsthma
University of Colorado, Denver60 enrolled1 locationNCT03885245
Recruiting
Phase 2
Anti Inflammatory Lipid Mediators in Asthma Lipid Anti-Inflammtory Mediators in Asthma
ObesityAsthma
University of Colorado, Denver60 enrolled1 locationNCT03762395