Phase 3 Pancreatic Cancer Clinical Trials

28 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 120 of 28 trials

Recruiting
Phase 3

A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer

Pancreatic CancerMetastatic Pancreatic CancerMetastatic Pancreatic Adenocarcinoma
Astellas Pharma Global Development, Inc.614 enrolled2 locationsNCT07409272
Recruiting
Phase 3

A Phase III Study of Ivonescimab + Chemo With/Without AK117 in Metastatic Pancreatic Cancer

Pancreatic Cancer
Akeso999 enrolled3 locationsNCT06953999
Recruiting
Phase 3

Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations

Stage III Pancreatic Cancer AJCC v8Stage IV Pancreatic Cancer AJCC v8Unresectable Pancreatic Adenocarcinoma+2 more
SWOG Cancer Research Network94 enrolled196 locationsNCT06998940
Recruiting
Phase 3

Polymeric Micellar Paclitaxel for Metastatic Pancreatic Cancer

Pancreatic Cancer Metastatic
Shanghai Yizhong Pharmaceutical Co., Ltd.416 enrolled2 locationsNCT06752811
Recruiting
Phase 3

Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer

Stage II Pancreatic Cancer AJCC v8Stage III Pancreatic Cancer AJCC v8Stage IV Pancreatic Cancer AJCC v8+1 more
NRG Oncology356 enrolled242 locationsNCT06958328
Recruiting
Phase 3

The Effect of Kinisoquin™ on Thromboembolic Events in Patients With Metastatic or Locally Advanced Pancreatic Cancer

Metastatic Pancreatic CancerVenous ThromboembolismLocally Advanced Pancreatic Adenocarcinoma
Quercis Pharma AG480 enrolled3 locationsNCT06861088
Recruiting
Phase 3

Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)

Pancreatic CancerPDACPDAC - Pancreatic Ductal Adenocarcinoma+2 more
Revolution Medicines, Inc.500 enrolled7 locationsNCT07252232
Recruiting
Phase 2Phase 3

A Phase II/III Trial to Evaluate the Efficacy and Safety of Surufatinib Combined With Camrelizumab, Nab-paclitaxel, and Gemcitabine in Metastatic Pancreatic Cancer

Metastatic Pancreatic Cancer
Hutchmed502 enrolled2 locationsNCT06361888
Recruiting
Phase 3

Irinotecan Hydrochloride Liposome Injection (II)in Combination With Oxaliplatin, 5-FU/LV Versus AG for First-line Treatment of Metastatic Pancreatic Cancer

First-line Treatment of Metastatic Pancreatic Cancer
Jiangsu HengRui Medicine Co., Ltd.662 enrolled1 locationNCT07238283
Recruiting
Phase 2Phase 3

Study of NABPLAGEM vs. Nab-Paclitaxel/Gemcitabine in BRCA1/2 or PALB2 Pancreatic Cancer

PALB2 Gene MutationPancreatic Cancer, Advanced or MetastaticBRCA1/2 Mutation
University Health Network, Toronto10 enrolled1 locationNCT06783140
Recruiting
Phase 3

Intra-arterial Gemcitabine vs. IV Gemcitabine and Nab-Paclitaxel Following Radiotherapy for LAPC

Locally Advanced Pancreatic Cancer
RenovoRx190 enrolled42 locationsNCT03257033
Recruiting
Phase 3

A Study to Compare QLS31905 and Chemotherapy With Placebo and Chemotherapy in Participants With Pancreatic Cancer

Pancreatic Cancer
Qilu Pharmaceutical Co., Ltd.602 enrolled1 locationNCT07079228
Recruiting
Phase 3

Tissue Adhesive Glue Modified Cyanoacrylate (Glubran® 2) in Soft Pancreas

Pancreatic CancerCholangiocarcinomaPancreatic Ductal Adenocarcinoma+4 more
Minia University194 enrolled1 locationNCT07155525
Recruiting
Phase 3

Neoadjuvant vs Upfront Surgery for Resectable Pancreatic Cancer and Periampullary Cancer

Pancreas CancerPancreas AdenocarcinomaPancreatic Cancer Resectable+3 more
Minia University262 enrolled1 locationNCT07081360
Recruiting
Phase 3

A Multicenter Study of IBI343 Monotherapy Versus Placebo in Subjects With Previously Treated, Claudin (CLDN) 18.2-positive, Pancreatic Cancer(G-HOPE-002)

Pancreatic Cancer
Innovent Biologics (Suzhou) Co. Ltd.201 enrolled1 locationNCT07066098
Recruiting
Phase 2Phase 3

Pancreatic Cancer Diagnosis With FAPI-PET Imaging

Pancreatic CancerFAPIPositron Emission Tomography+5 more
Turku University Hospital100 enrolled1 locationNCT07098598
Recruiting
Phase 3

Clinical Study of Tumor Treating Fields Combined with Gemcitabine and Albumin-bound Paclitaxel in the First-line Treatment of Locally Advanced Pancreatic Cancer

Locally Advanced Pancreatic Cancer
Jiangsu Healthy Life Innovation Medical Technology Co., Ltd512 enrolled5 locationsNCT05653453
Recruiting
Phase 3

Adjuvant Chemoradiotherapy Versus Chemotherapy for Pancreatic Cancer (ADJUPANC)

Pancreatic Cancer
Changhai Hospital770 enrolled1 locationNCT06427447
Recruiting
Phase 3

NeoFOL-R Trial (Perioperative Versus Adjuvnat FOLFIRINOX in Resectable Pancreatic Cancer)

Neoadjuvant ChemotherapyResectable Pancreatic CancerEffects of Chemotherapy
Seoul National University Hospital609 enrolled2 locationsNCT05529940
Recruiting
Phase 2Phase 3

Vitamin C Plus Cordyceps to Chemotherapy Related Anemia in Pancreatic Cancer

Pancreatic Cancer
Fudan University50 enrolled1 locationNCT06601283