Phase 2 Parkinson Disease Clinical Trials

37 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 37 trials

Recruiting
Phase 2Phase 3

Montelukast in Parkinson Disease

Parkinson Disease
Mostafa Bahaa60 enrolled1 locationNCT06113640
Recruiting
Phase 1Phase 2

Safety and Tolerability of IRL757 in Participants With Parkinson's Disease and Apathy

SafetyPARKINSON DISEASE (Disorder)Apathy
Integrative Research Laboratories AB75 enrolled13 locationsNCT07461220
Recruiting
Phase 2

A Trial to Test the Use of Dapansutrile, an Anti-inflammatory Medication, in People With Parkinson's Disease

Parkinson Disease
Cambridge University Hospitals NHS Foundation Trust36 enrolled1 locationNCT07157735
Recruiting
Phase 2

Pyridostigmine for the Treatment of Constipation in Parkinson Disease

ConstipationParkinson Disease
University of Vermont Medical Center16 enrolled1 locationNCT05603715
Recruiting
Phase 2

A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

Parkinson DiseaseParkinsonParkinson Disease, Idiopathic+2 more
Neuron23 Inc.150 enrolled69 locationsNCT06680830
Recruiting
Phase 2

Safety and Pharmacodynamic Effects of BIIB122 in Participants With LRRK2-Associated Parkinson's Disease (LRRK2-PD)

Parkinson Disease
Denali Therapeutics Inc.50 enrolled20 locationsNCT06602193
Recruiting
Phase 1Phase 2

Feasibility Study Assessing the Effect of Carbidopa/Levodopa Ratio on Orthostatic Hypotension in Multiple System Atrophy - Parkinsonian Type and Parkinson Disease.

Parkinson DiseaseOrthostatic Hypotension, DysautonomicMulti-system Atrophy - Parkinsonian Type
Julien Bally36 enrolled2 locationsNCT06831500
Recruiting
Phase 1Phase 2

Virtual tES Device Treatment for Parkinson's Disease Motor Symptoms

PARKINSON DISEASE (Disorder)
U: The Mind Company30 enrolled1 locationNCT07182058
Recruiting
Phase 2Phase 3

Fexofenadine as Adjuvant Therapy in Parkinson Disease

Parkinson Disease
Tanta University46 enrolled1 locationNCT06785298
Recruiting
Phase 2Phase 3

A Study to Determine if BHV-8000 is Effective, Safe and Tolerable as a Treatment for Adults Living With Early Parkinson's Disease

Parkinson Disease
Biohaven Therapeutics Ltd.550 enrolled15 locationsNCT06976268
Recruiting
Phase 2

Wearable Biofeedback for Swallowing Disorders Rehabilitation in Stroke and Parkinson Disease

StrokeParkinson DiseaseDysphagia
Purdue University120 enrolled1 locationNCT06638944
Recruiting
Phase 2

D-SPARK: A Clinical Trial of D-Serine for Modifying Parkinson's Disease Progression

Parkinson's DiseaseParkinson Disease (PD)
Haukeland University Hospital100 enrolled11 locationsNCT07312110
Recruiting
Phase 1Phase 2

Clinical Study to Evaluate XS411 in Treatment of Early-onset Parkinson's Disease

Parkinson Disease (PD)
XellSmart Bio-Pharmaceutical (Suzhou) Co., Ltd.90 enrolled1 locationNCT07166757
Recruiting
Phase 2Phase 3

Vinpocetine in Patients With Parkinsonian Disease

Parkinson Disease
Tanta University60 enrolled1 locationNCT07229664
Recruiting
Phase 1Phase 2

Celecoxib in Parkinson Disease as Adjuvant Therapy

Parkinson Disease
Tanta University80 enrolled1 locationNCT07246278
Recruiting
Phase 2

A Study of AAV2-GDNF in Adults With Moderate Parkinson's Disease (REGENERATE-PD)

Parkinson Disease
AskBio Inc127 enrolled39 locationsNCT06285643
Recruiting
Phase 2Phase 3

Metformin in Parkinson Disease

Parkinson Disease
Tanta University60 enrolled1 locationNCT07229651
Recruiting
Phase 1Phase 2

Phase 2 Trial of Tributyrin in People With Parkinson's Disease and Cognitive Impairments

Parkinson DiseaseParkinson Disease Dementia
Prabesh Kanel45 enrolled1 locationNCT07154511
Recruiting
Phase 2

Clinical Trial Evaluating the Efficacy and Safety of AGB101 for Treatment of Parkinson's Disease Related Psychosis

Parkinson Disease Psychosis
Johns Hopkins University30 enrolled1 locationNCT05824728
Recruiting
Phase 1Phase 2

Evaluation of Long-term Safety in Parkinsonian Patients With Intracerebroventricular Administration of A-dopamine (Anaerobic Dopamine)

Parkinson Disease
University Hospital, Lille1 enrolled1 locationNCT07214285