Phase 3 Prostate Cancer Clinical Trials
49 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 49 trials
Recruiting
Phase 3
64Cu-SAR-bisPSMA Positron Emission Tomography: A Phase 3 Study of Participants With Biochemical Recurrence of Prostate Cancer
Prostate CancerCryotherapyProstate Cancer Recurrent+3 more
Clarity Pharmaceuticals Ltd220 enrolled28 locationsNCT06970847
Recruiting
Phase 2Phase 3
Open-label Study Comparing AAA817 Versus Standard of Care in the Treatment of Previously Treated PSMA-positive mCRPC Adults Who Have Disease Progressed on or After [177Lu]Lu-PSMA Targeted Therapy
Prostate Cancer
Novartis Pharmaceuticals443 enrolled52 locationsNCT06780670
Recruiting
Phase 3
Adjuvant Curcumin to Assess Recurrence Free Survival in Patients Who Have Had a Radical Prostatectomy
Prostate Cancer
yair lotan608 enrolled1 locationNCT02064673
Recruiting
Phase 3
Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy
Prostate CancerProstatic Neoplasms
Clarity Pharmaceuticals Ltd383 enrolled27 locationsNCT06056830
Recruiting
Phase 3
A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)
Prostate CancerProstatic Neoplasms
Merck Sharp & Dohme LLC1,440 enrolled274 locationsNCT06925737
Recruiting
Phase 3
A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation
Prostate Cancer
AstraZeneca700 enrolled328 locationsNCT06952803
Recruiting
Phase 3
This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.
Prostate CancerCancer of the ProstateHormone Sensitive Prostate Cancer+1 more
Pfizer1,000 enrolled188 locationsNCT07028853
Recruiting
Phase 2Phase 3
PSMA-PET Imaging for Detecting Early Metastatic Prostate Cancer in Men w/ High Decipher Test Scores
Prostate CancerRecurrent Prostate Cancer
H. Lee Moffitt Cancer Center and Research Institute60 enrolled1 locationNCT03495427
Recruiting
Phase 3
Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC
Prostate Cancer
Novartis Pharmaceuticals940 enrolled55 locationsNCT06855277
Recruiting
Phase 3
Robotic Opioid-free Prostatectomy Enhanced Strategy (ROPES)
Prostate CancerOpioid Consumption, PostoperativeMultimodal Analgesia+2 more
Brigham and Women's Hospital300 enrolled2 locationsNCT07427043
Recruiting
Phase 3
Copper Cu 64 PSMA I&T PET Imaging in Men With Newly Diagnosed Prostate Cancer
Prostate CancerProstate Adenocarcinoma
Curium US LLC439 enrolled43 locationsNCT06235151
Recruiting
Phase 3
Stereotactic Ablative Radiotherapy (SABR) for the Treatment of Patients With Metastatic Cancer, ID-COMET Trial
Prostate CancerLung CancerColo-rectal Cancer+1 more
Roswell Park Cancer Institute800 enrolled1 locationNCT06563388
Recruiting
Phase 3
Diagnostic Performance of [18F]PSMA-1007 PET/CT Imaging in Patients With Newly-Diagnosed Prostate Cancer
Prostate Cancer
ABX advanced biochemical compounds GmbH380 enrolled18 locationsNCT06122584
Recruiting
Phase 3
Androgen Suppression Combined With Nodal Irradiation and Dose Escalated Prostate Treatment
Prostate Cancer
Canadian Cancer Trials Group710 enrolled53 locationsNCT06235697
Recruiting
Phase 3
Vascular Optimized Radiotherapy Tuned to Critical Structures for Erectile Function Using High-Precision X-Ray Treatment
Prostate Cancer
Jonsson Comprehensive Cancer Center200 enrolled1 locationNCT07293585
Recruiting
Phase 2Phase 3
4-aminopyridine Treatment for Nerve Injury
Prostate CancerNerve Injury
John Elfar70 enrolled2 locationsNCT03701581
Recruiting
Phase 3
Apa/Enza-short Study: Shorter Treatment With Androgen Receptor Pathway Inhibitor in Patients With Low-volume Metastatic Castration-sensitive Prostate Cancer
Prostate Cancer
Nick Beije400 enrolled26 locationsNCT07260435
Recruiting
Phase 2Phase 3
Trop2-targeted immunoPET Imaging of Solid Tumors
Liver CancerOvarian CancerCervical Cancer+11 more
RenJi Hospital400 enrolled1 locationNCT06851663
Recruiting
Phase 3
PROSTATE-IQ: Parallel RandOmized STudy of Personalized Apalutamide Treatment and Evaluation to Improve Quality of Life in Post-Operative Radiation With Androgen Axis Suppression. A Phase III Multi-center Study for Men With Detectable PSA After Prostatectomy for Prostate Cancer.
Prostate CancerAndrogen Axis SuppressionProstatectomy
M.D. Anderson Cancer Center120 enrolled3 locationsNCT06274047
Recruiting
Phase 2Phase 3
AMNIOX CORD Study - Radical Prostatectomy With and Without Cryopreserved Umbilical Cord Allograft
Prostate Cancer
Hackensack Meridian Health100 enrolled1 locationNCT04263025