Phase 2 PTSD Clinical Trials

20 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 20 trials

Recruiting
Phase 2

Group vs Individual MDMA-Assisted Therapy for PTSD After the October 7, 2023 Events

PTSD
Sheba Medical Center168 enrolled2 locationsNCT07469098
Recruiting
Phase 2

Induction of Dreaming With EEG and Anesthesia for Post-traumatic Stress Disorder

Post Traumatic Stress DisorderPTSD
Stanford University42 enrolled1 locationNCT06577636
Recruiting
Phase 2

Phase IIa Trial of a Selective Glucocorticoid Receptor Antagonist in the Treatment of Veterans With Posttraumatic Stress Disorder (PTSD) (Seven Study)

PTSD
VA Office of Research and Development40 enrolled2 locationsNCT04452500
Recruiting
Phase 2

State-Funded Trial Assessing Recovery and Long-Term Impact of Guided Psilocybin for Healing Trauma

PTSD
Baylor College of Medicine15 enrolled1 locationNCT06888128
Recruiting
Phase 2

Oxytocin to Enhance Integrated Treatment for AUD and PTSD

Alcohol Use DisorderPTSD
Medical University of South Carolina180 enrolled1 locationNCT04523922
Recruiting
Phase 2

Determining the Potential for Efficacy of OTX-601 in Reducing PTSD Symptoms

Post Traumatic Stress DisorderPTSD
Oui Therapeutics, Inc.40 enrolled1 locationNCT07316088
Recruiting
Phase 2

Ayahuasca, Esketamine and PTSD

Posttraumatic Stress Disorder (PTSD)
University of Sao Paulo10 enrolled1 locationNCT07317206
Recruiting
Phase 2Phase 3

Software as a Medical Device for the Treatment of Patients With PTSD

Post Traumatic Stress Disorder (PTSD)
Otsuka Medical Devices Co., Ltd. Japan52 enrolled35 locationsNCT06589505
Recruiting
Phase 2

Veterans' Cognitive Function, Mental Health, and Quality of Life After Hyperbaric Oxygen Therapy

PTSD - Post Traumatic Stress DisorderTBI (Traumatic Brain Injury)Post Concussive Syndrome
Summit Hyperbarics and Wellness54 enrolled1 locationNCT07214415
Recruiting
Phase 2

A Study to Evaluate Effects on Sleep and Safety of RE03 in PTSD Patients With Sleep Disturbances

Sleep Disturbances and InsomniaPosttraumatic Stress Disorder (PTSD)
Reconnect Labs24 enrolled1 locationNCT06685965
Recruiting
Phase 2

Intranasal Insulin for Posttraumatic Stress Disorder

PTSD
VA Connecticut Healthcare System20 enrolled1 locationNCT04044534
Recruiting
Phase 2

Psilocybin With Psychological Support (Psi-PS) for Military Veterans and First Responders With Co-occurring PTSD & Alcohol Use Disorder (AUD)

PTSDAlcohol Use Disorder (AUD)
Nathan Brashares Sackett40 enrolled1 locationNCT06853912
Recruiting
Phase 2

MDMA-assisted Cognitive Processing Therapy Versus Cognitive Processing Therapy for Veterans With Severe Posttraumatic Stress Disorder

PTSD
Patricia Suppes30 enrolled1 locationNCT05837845
Recruiting
Phase 2

Suvorexant for Treatment of AUD and PTSD

InsomniaPost Traumatic Stress Disorder (PTSD)Alcohol Use Disorder (AUD)
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance76 enrolled2 locationsNCT06679062
Recruiting
Phase 2

Examining Intranasal Oxytocin Augmentation of Brief Couples Therapy for Veterans With PTSD

Post Traumatic Stress Disorder (PTSD)
VA Office of Research and Development240 enrolled1 locationNCT06194851
Recruiting
Phase 2

Safety and Efficacy of Cannabidiol (CBD) for Symptoms of PTSD in Adults

PTSD
University of Nebraska180 enrolled1 locationNCT05269459
Recruiting
Phase 2Phase 3

Glecaprevir/Pibrentasvir for Post-traumatic Stress Disorder

PTSD
White River Junction Veterans Affairs Medical Center92 enrolled1 locationNCT05637879
Recruiting
Phase 2

REVERSE: Improving Treatment-resistant Post Traumatic Stress Disorder (PTSD) with Glucocorticoid Receptor (GR) Antagonism

Treatment-resistant PTSD
Christiaan Vinkers60 enrolled1 locationNCT06689254
Recruiting
Phase 2

Neuromodulation of the Hippocampus to Reduce Intrusive Re-Experiencing in PTSD: A Randomized Controlled Trial

PTSD - Post Traumatic Stress DisorderIntrusive Memories of Traumatic Event(s)
Tel Aviv University60 enrolled1 locationNCT06639061
Recruiting
Phase 2

MDMA-assisted Prolonged Exposure Therapy for Comorbid Alcohol Use Disorder and Post-traumatic Stress Disorder

Comorbidities and Coexisting ConditionsPost Traumatic Stress DisorderAlcohol Use Disorder+2 more
University of Sydney120 enrolled2 locationsNCT05709353