Phase 1 Schizophrenia Clinical Trials
14 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–14 of 14 trials
Recruiting
Phase 1Phase 2
Tolerability of MDMA in Schizophrenia
Schizophrenia
Anya Bershad, MD, PhD20 enrolled1 locationNCT05770375
Recruiting
Phase 1Phase 2
Cromoglicate Adjunctive Therapy for Outpatients With Schizophrenia
SchizophreniaSchizo Affective Disorder
Vishwajit Nimgaonkar, MD PhD160 enrolled1 locationNCT03794076
Recruiting
Phase 1
Evaluating Safety, Tolerability and Pharmacokinetic of Multiple Ascending Doses of VV119
Schizophrenia
Vigonvita Life Sciences40 enrolled4 locationsNCT06504290
Recruiting
Phase 1
A Study to Evaluate the Dose Levels, Safety, and Drug Levels of Single KarXT Intramuscular Injection in Participants With Schizophrenia
Schizophrenia
Bristol-Myers Squibb48 enrolled8 locationsNCT07061288
Recruiting
Phase 1Phase 2
Pharmacokinetics, Safety, Tolerability and Efficacy of a Subcutaneous Long-Acting Injection of Cariprazine (Cariprazine Depot) in Subjects Eligible for Treatment With Oral Cariprazine
SchizophreniaMajor Depressive Disorder (MDD)Bipolar 1 Disorder
Mapi Pharma Ltd.24 enrolled3 locationsNCT07185815
Recruiting
Phase 1
A Phase 1 MAD Study to Evaluate the Safety and Tolerability of LY03020
SchizophreniaAlzheimer's Disease Psychosis
Luye Pharma Group Ltd.40 enrolled1 locationNCT07230652
Recruiting
Phase 1
The Purpose of This Study is to Determine the Safety, Tolerability, and Pharmacokinetics of Brexpiprazole Long-acting Injection Following a Single Administration in Healthy Subjects/Patients With Schizophrenia.
Schizophrenia Disorders
Sichuan Kelun Pharmaceutical Research Institute Co., Ltd.56 enrolled1 locationNCT06674694
Recruiting
Phase 1
Genetics of Cannabis Use Disorder and Cannabinoid Response in Humans
SchizophreniaCannabis Use Disorder
Yale University215 enrolled1 locationNCT06058702
Recruiting
Phase 1
Study of the Safety, Tolerability, Pharmacokinetics and Food Effects of VV119 Capsules in Chinese Healthy Volunteers
Schizophrenia
Vigonvita Life Sciences82 enrolled1 locationNCT06105151
Recruiting
Phase 1
Proposal To Develop A Rapid And Cost-Effective Diagnostic Test For Schizophrenia
Schizophrenia
University of Arizona24 enrolled1 locationNCT03781115
Recruiting
Phase 1
Alexithymia Intervention for Suicide
SchizophreniaPost Traumatic Stress DisorderSuicide+2 more
VA Office of Research and Development40 enrolled1 locationNCT05724953
Recruiting
Phase 1Phase 2
Acetazolamide for Treatment Resistant Schizophrenia
SchizophreniaSchizo Affective Disorder
Vishwajit Nimgaonkar, MD PhD60 enrolled2 locationsNCT04887792
Recruiting
Phase 1
Imaging Synapses With [11C] UCB-J in the Human Brain
Schizophrenia
Davidzon, Guido, M.D.60 enrolled2 locationsNCT04038840
Recruiting
Phase 1
Determining Efficacy and Safety of BXCL501 in Agitation Associated With Pediatric Schizophrenia and Bipolar Disorder
SchizophreniaSchizo Affective DisorderBipolar Disorder I+2 more
BioXcel Therapeutics Inc140 enrolled5 locationsNCT05025605