Phase 1 Solid Tumor Clinical Trials
33 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 33 trials
Recruiting
Phase 1Phase 2
A Study to Evaluate the Safety, Tolerability, and Efficacy of MORAb-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (FRα)-Targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types
Solid Tumor
Eisai Inc.182 enrolled58 locationsNCT04300556
Recruiting
Phase 1
Phase I Study of Tolododekin Alfa (ANK-101) in Advanced Solid Tumors
Advanced Solid TumorMetastatic Solid TumorSolid Tumor+4 more
Ankyra Therapeutics, Inc97 enrolled5 locationsNCT06171750
Recruiting
Phase 1Phase 2
A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations
Breast CancerOvarian CancerCervical Cancer+5 more
Terremoto Biosciences Inc.205 enrolled14 locationsNCT07109726
Recruiting
Phase 1Phase 2
SMP-3124LP in Adults With Advanced Solid Tumors
Solid Tumor
Sumitomo Pharma America, Inc.120 enrolled10 locationsNCT06526819
Recruiting
Phase 1
A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors
Solid Tumor
Astellas Pharma Inc364 enrolled12 locationsNCT07094204
Recruiting
Phase 1
A Clinical Study of the Safety and Effectiveness of an Investigational Cell Therapy Given With and Without an Investigational RNA-based Vaccine in Patients With Organ Tumors
Solid Tumor
BioNTech Cell & Gene Therapies GmbH214 enrolled12 locationsNCT04503278
Recruiting
Phase 1
A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors
Ovarian CancerOvarian CarcinomaAdvanced Solid Tumor+8 more
NiKang Therapeutics, Inc.150 enrolled19 locationsNCT06586957
Recruiting
Phase 1Phase 2
Study of MCLA-129, a Human Bispecific EGFR and cMet Antibody, in Patients With Advanced NSCLC and Other Solid Tumors
Solid Tumor
Betta Pharmaceuticals Co., Ltd.400 enrolled87 locationsNCT04930432
Recruiting
Phase 1Phase 2
Phase 1/2 Study to Evaluate TH9619 in the Treatment of Advanced Solid Tumors
Squamous Cell Carcinoma of Head and NeckSolid TumorColorectal Cancer (CRC)
One-carbon Therapeutics AB43 enrolled4 locationsNCT07151040
Recruiting
Phase 1
A Study of BL-M17D1 in Patients With Locally Advanced or Metastatic HER2 Positive/Negative Breast Cancer and Other Solid Tumors
Breast CancerSolid Tumor
Sichuan Baili Pharmaceutical Co., Ltd.20 enrolled2 locationsNCT06503783
Recruiting
Phase 1
A Study of GNC-077 in Patients With Locally Advanced or Metastatic Breast Cancer and Other Solid Tumors
Breast CancerSolid Tumor
Sichuan Baili Pharmaceutical Co., Ltd.20 enrolled1 locationNCT06609187
Recruiting
Phase 1
A Study of GNC-077 in Patients With Locally Advanced or Metastatic Non-small-cell Lung Cancer and Other Solid Tumors
Non-small Cell Lung CancerSolid Tumor
Sichuan Baili Pharmaceutical Co., Ltd.20 enrolled1 locationNCT06612840
Recruiting
Phase 1
Study to Assess the Effect of OCT-598 in Patients With Advanced Solid Tumors
Breast CancerHead and Neck CancerSolid Tumor
Oscotec Inc.51 enrolled3 locationsNCT07358806
Recruiting
Phase 1
A Study of GC203 TIL in Advanced Malignant Solid Tumors
Breast CancerLung CancerSolid Tumor+2 more
Shanghai Juncell Therapeutics18 enrolled1 locationNCT06375187
Recruiting
Phase 1Phase 2
Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
Non-small Cell Lung CancerMetastatic Lung CancerMetastatic Lung Non-Small Cell Carcinoma+18 more
Institut de Recherches Internationales Servier554 enrolled10 locationsNCT05786924
Recruiting
Phase 1
Study of IDE397 in Participants With Solid Tumors Harboring MTAP Deletion
Solid Tumor
IDEAYA Biosciences180 enrolled39 locationsNCT04794699
Recruiting
Phase 1
Indocyanine Green (ICG) Guided Tumor Resection
Solid TumorNeoplastic Disease
St. Jude Children's Research Hospital230 enrolled1 locationNCT04084067
Recruiting
Phase 1Phase 2
A Phase 1/2, Open-label, Multicenter, FIH Study to Evaluate Safety, Tolerability, PK and Anti-tumor Activity of YH42946
Solid TumorNSCLC (Non-small Cell Lung Cancer)
Yuhan Corporation161 enrolled8 locationsNCT06616766
Recruiting
Phase 1
A Study of BL-B01D1 in Patients With Unresectable Locally Advanced or Metastatic Breast Cancer and Other Solid Tumors
Breast CancerSolid Tumor
Sichuan Baili Pharmaceutical Co., Ltd.36 enrolled2 locationsNCT05470348
Recruiting
Phase 1Phase 2
Optimizing and Personalising Azacitidine Combination Therapy for Treating Solid Tumours QPOP and CURATE.AI
Breast CancerSolid TumorGastrointestinal Cancer
National University Hospital, Singapore10 enrolled1 locationNCT05381038