Phase 2 Alzheimer Disease Clinical Trials

45 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 45 trials

Recruiting
Phase 2

Novel Augmentation of DAOIB and Antioxidant for Early Dementia

Alzheimer DiseaseMild Cognitive Impairment
Chang Gung Memorial Hospital80 enrolled1 locationNCT06467539
Recruiting
Phase 2

Levetiracetam for Persons at Risk for Alzheimer's Disease

Hippocampal HyperactivationProdromal Alzheimer Disease
Sunnybrook Health Sciences Centre40 enrolled2 locationsNCT07477431
Recruiting
Phase 2

Allopregnanolone Regenerative Therapeutic for Mild Alzheimer's Disease

Alzheimer DementiaLate Onset Alzheimer DiseaseNeurodegenerative Diseases
University of Arizona100 enrolled10 locationsNCT04838301
Recruiting
Phase 1Phase 2

Nicotinic Acid for the Treatment of Alzheimer's Disease

Alzheimer Disease
Indiana University30 enrolled1 locationNCT06582706
Recruiting
Phase 2

Repurposing Siponimod for Alzheimer's Disease

Alzheimer DiseaseCognitive Impairment, MildMild Alzheimer Disease+1 more
St. Joseph's Hospital and Medical Center, Phoenix105 enrolled1 locationNCT06639282
Recruiting
Phase 2

A Trial to Evaluate the Safety and Efficacy of Benfotiamine in Patients With Early Alzheimer's Disease (BenfoTeam)

Alzheimer Disease
Alzheimer's Disease Cooperative Study (ADCS)406 enrolled47 locationsNCT06223360
Recruiting
Phase 2

Exercise to Improve Brain Health in Older African Americans

Cognitive ChangeAlzheimer DiseaseAging+1 more
Rutgers, The State University of New Jersey280 enrolled1 locationNCT05597124
Recruiting
Phase 2

A Study of AMDX-2011P in Participants With Alzheimer's Disease

Alzheimer Disease
Amydis Inc.25 enrolled1 locationNCT06514001
Recruiting
Phase 2

ALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older Adults

Cognitive DysfunctionAlzheimer DiseaseFatty Acids, Omega-3+3 more
Michal Schnaider Beeri, Ph.D.20 enrolled1 locationNCT07392723
Recruiting
Phase 2

Cannabidiol Medication Intervention Trial

Alzheimer Disease
Sunnybrook Health Sciences Centre40 enrolled5 locationsNCT06014424
Recruiting
Phase 2

Senicapoc in Alzheimer's Disease

Alzheimer DiseaseMild Cognitive Impairment
University of California, Davis55 enrolled2 locationsNCT04804241
Recruiting
Phase 2

Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease

Alzheimer DiseaseAgitation
Celgene120 enrolled52 locationsNCT06808984
Recruiting
Phase 2

Clinical Trial on Agitation in Alzheimer's Dementia

Alzheimer DiseaseAggressionAgitation,Psychomotor+2 more
IGC Pharma, LLC164 enrolled28 locationsNCT05543681
Recruiting
Phase 1Phase 2

Deep Repetitive Transcranial Magnetic Stimulation (rTMS) of the Precuneus for Alzheimer Disease (AD)

Alzheimer DiseaseAlzheimer&Amp;Amp;#39;s DiseaseDementia Alzheimer Type+4 more
University of California, Los Angeles54 enrolled1 locationNCT06597942
Recruiting
Phase 2

Bumetanide in Patients With Alzheimer's Disease

Alzheimer Disease
Stanford University40 enrolled1 locationNCT06052163
Recruiting
Phase 2

Phase II Trial to Evaluate Safety and Efficacy of GM-CSF/Sargramostim in Alzheimer's Disease

Alzheimer Disease
University of Colorado, Denver42 enrolled1 locationNCT04902703
Recruiting
Phase 2

Daridorexant for Alzheimer Disease Prevention

Alzheimer Disease (AD)
Douglas Mental Health University Institute240 enrolled1 locationNCT07213349
Recruiting
Phase 2

Sleep Trial to Prevent Alzheimer's Disease

SleepAlzheimer Disease
Washington University School of Medicine200 enrolled1 locationNCT04629547
Recruiting
Phase 2

Combined Brain Stimulation and Methylphenidate Treatment for Apathy in Dementia

Alzheimer DiseaseAlzheimer DementiaAlzheimer Dementia (AD)+3 more
Sunnybrook Health Sciences Centre12 enrolled1 locationNCT07279740
Recruiting
Phase 1Phase 2

Study of ARO-MAPT-SC in Healthy Subjects and Subjects With Early Alzheimer's Disease

Alzheimer DiseaseAlzheimer Disease, Early Onset
Arrowhead Pharmaceuticals112 enrolled1 locationNCT07221344