Phase 4 Cancer Clinical Trials
110 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 110 trials
Recruiting
Phase 4
Study Evaluating Safety, Tolerability, and Metabolism of Niraparib
Ovarian Cancer
University of Miami70 enrolled2 locationsNCT06412120
Recruiting
Phase 4
SIS-Reinforced vs. Conventional Anastomosis for Mid-to-Low Rectal Cancer: A Multicenter RCT on Anastomotic Leak
Rectal Cancer
Beijing Chao Yang Hospital966 enrolled1 locationNCT07209787
Recruiting
Phase 4
Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical Cancer
Cervical Cancer
Pfizer100 enrolled78 locationsNCT06952660
Recruiting
Phase 4
A Study to Investigate Mechanisms of Resistance to Breast Cancer Therapies
Breast Cancer
Hoffmann-La Roche320 enrolled28 locationsNCT06274515
Recruiting
Phase 4
Pharmacokinetic Study of Skeletal Muscle Area-based Paclitaxel Infusion in Patients With Cancer
Breast CancerEsophageal CancerMetastatic Gastric Cancer
University of Michigan Rogel Cancer Center22 enrolled1 locationNCT05183126
Recruiting
Phase 4
A Study of Toripalimab in Combination With Cisplatin and Gemcitabine in Participants With Recurrent Metastatic Nasopharyngeal Cancer
Nasopharyngeal Cancer Recurrent
Coherus Oncology, Inc.100 enrolled13 locationsNCT06457503
Recruiting
Phase 4
A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer
Colorectal, Cancer
Takeda78 enrolled45 locationsNCT06562543
Recruiting
Phase 4
Erector Spinae Block for Thoracic Surgery
Thoracic CancerPulmonary CancerThoracic Neoplasms+2 more
George Washington University70 enrolled1 locationNCT05521789
Recruiting
Phase 4
An Investigational Scan (64Cu-DOTA-Trastuzumab PET/MRI) in Imaging Patients With HER2+ Breast Cancer With Brain Metastasis
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaMetastatic Malignant Neoplasm in the Brain
City of Hope Medical Center10 enrolled1 locationNCT05376878
Recruiting
Phase 4
Enfortumab Vedotin and Pembrolizumab With Cystectomy and/or Ureterectomy for Locally Advanced or Metastatic Bladder and Upper Urothelial Tract Cancer, CAST-AI Trial
Metastatic Bladder Urothelial CarcinomaStage IV Bladder Cancer AJCC v8Metastatic Renal Pelvis and Ureter Urothelial Carcinoma+4 more
Mayo Clinic75 enrolled1 locationNCT06764095
Recruiting
Phase 4
Evaluating Dose Timing (Morning vs Evening) of Endocrine-based Therapies in Metastatic Breast and Prostate Cancers
Metastatic Breast CancerMetastatic Prostate Cancer
Ottawa Hospital Research Institute50 enrolled3 locationsNCT07252726
Recruiting
Phase 4
A Study of Revaree Plus in People With Breast Cancer
Breast CancerStage III Breast CancerStage I Breast Cancer+5 more
Memorial Sloan Kettering Cancer Center60 enrolled7 locationsNCT07042581
Recruiting
Phase 4
Study Aiming to Compare the Plasma Exposure of the Payload (Free-DXd) in Patients Treated by T-DXd for Locally Advanced or Metastatic Breast Cancer According to Their BMI.
Locally Advanced or Metastatic Breast Cancers
Institut Claudius Regaud210 enrolled10 locationsNCT07195344
Recruiting
Phase 4
Dabrafenib and/or Trametinib Rollover Study
MelanomaNon-small Cell Lung CancerSolid Tumor+2 more
Novartis Pharmaceuticals100 enrolled28 locationsNCT03340506
Recruiting
Phase 4
A Study to Learn More About How Safe Darolutamide is and How Well it Works Under Real World Conditions When Taken in Addition to Standard Androgen Deprivation Therapy (ADT) in Indian Participants With High-risk Non-metastatic Castration-resistant Prostate Cancer (nmCRPC)
Non-metastatic Castration-resistant Prostate Cancer
Bayer50 enrolled25 locationsNCT05348876
Recruiting
Phase 4
EBUS-TBNA vs Transbronchial Mediastinal Cryobiopsy for Adequacy of Next Generation Sequencing
Lung Cancer
Vanderbilt-Ingram Cancer Center250 enrolled1 locationNCT06105801
Recruiting
Phase 4
Pilot of 18F-DCFPyL-PSMA PET in mCRPC Patients Receiving 117Lu-Vipivotide Tetraxetan
Prostate CancerMetastatic Castration-resistant Prostate CancerMetastatic Castration-Resistant Prostate Carcinoma
Brigham and Women's Hospital30 enrolled2 locationsNCT06099093
Recruiting
Phase 4
Effect of HSD3B1 (1245C) Gene Mutation on Treatment of Stage I-III Breast Cancer
Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage I Breast Cancer AJCC v8+2 more
University of Washington68 enrolled1 locationNCT05183828
Recruiting
Phase 4
Abemaciclib Dose Escalation to Maintain Intensity (ADE-MI)
Breast Cancer
University of Illinois at Chicago50 enrolled3 locationsNCT06169371
Recruiting
Phase 4
Vesical Imaging-Reporting and Data System (VI-RADS) Followed by Photodynamic Trans-urethral Resection of Bladder Tumours (PDD-TURBT) to Avoid Secondary Resections (Re-TURBT) in Non-Muscle Invasive Bladder Cancers (NMIBCs)
Non Muscle Invasive Bladder CancerHigh Risk Non-Muscle Invasive Bladder Urothelial CarcinomaNon-Muscle Invasive Bladder Urothelial Carcinoma
University of Roma La Sapienza327 enrolled1 locationNCT05962541