Phase 2 Hypertension Clinical Trials
55 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 55 trials
Recruiting
Phase 2Phase 3
Study of QLS-111-FDC in Open-Angle Glaucoma or Ocular Hypertension
OAG - Open-Angle GlaucomaOHT - Ocular Hypertension
Qlaris Bio, Inc.36 enrolled1 locationNCT07354516
Recruiting
Phase 2
A Study to Learn About the Study Medicine (Called PF-07868489) in People With Pulmonary Arterial Hypertension Who Have Previously Participated in a Clinical Study With PF-07868489
Pulmonary Hypertension
Pfizer36 enrolled36 locationsNCT07073820
Recruiting
Phase 2
SGLT2i Improve Left Atrial Function in Patients With Paroxysmal Atrial Fibrillation, Hypertension and Abnormal Glucose Metabolism
HypertensionAtrial Fibrillation (AF)
Huashan Hospital66 enrolled1 locationNCT07482020
Recruiting
Phase 2
Spironolactone for Pulmonary Arterial Hypertension
Pulmonary Arterial Hypertension
National Institutes of Health Clinical Center (CC)70 enrolled1 locationNCT01712620
Recruiting
Phase 2
Study to Evaluate Sotatercept (MK-7962) in Children With Pulmonary Arterial Hypertension (PAH) (MK-7962-008)
Pulmonary Arterial Hypertension
Merck Sharp & Dohme LLC42 enrolled35 locationsNCT05587712
Recruiting
Phase 2Phase 3
Sildinafil in Pulmonary Hypertension-Rheumatic Chronic Valvular Disease(RCT)
Pulmonary HypertensionRheumatic Valvular Heart Disease
Sindh Institute of Cardiovascular Diseases100 enrolled1 locationNCT07462260
Recruiting
Phase 2
Extension Study of Sotatercept in People With Pulmonary Hypertension (MK-7962-023)
Hypertension, Pulmonary
Merck Sharp & Dohme LLC130 enrolled55 locationsNCT06814145
Recruiting
Phase 2
A Study of ROC-101 in Patients With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (ILD-PH) (ROCSTAR STUDY)
Pulmonary Arterial Hypertension PAHPulmonary Hypertension, Interstitial Lung Disease
AllRock Bio, Inc.40 enrolled11 locationsNCT07175038
Recruiting
Phase 1Phase 2
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
Healthy Volunteers, Pulmonary Arterial Hypertension
Novartis Pharmaceuticals232 enrolled29 locationsNCT06649110
Recruiting
Phase 2
A Phase IIb Study to Evaluate the Effect of Dapagliflozin in Combination With Baxdrostat Compared With Baxdrostat on Albuminuria in Participants With Chronic Kidney Disease and High Blood Pressure.
Chronic Kidney Disease and Hypertension
AstraZeneca218 enrolled70 locationsNCT07222917
Recruiting
Phase 2
A Trial of "APL-9796'' in Adults With Pulmonary Hypertension
Pulmonary Arterial Hypertension
Apollo Therapeutics Ltd48 enrolled5 locationsNCT06846554
Recruiting
Phase 1Phase 2
Umbilical Cord Blood CD19-BCMA CART Cell Therapy for SLE-LN, SSc, andpSS PAH.
Refractory Lupus NephritisSystemic SclerosisPrimary Sjogren's Syndrome Combined With Pulmonary Hypertension
Beijing GoBroad Hospital45 enrolled1 locationNCT06947473
Recruiting
Phase 1Phase 2
CD19-BCMA CART Cell Therapy for Refractory SLE-LN, SSc, and pSS-PAH
Refractory Lupus NephritisSystemic SclerosisPrimary Sjogren's Syndrome Combined With Pulmonary Hypertension
Beijing GoBroad Hospital45 enrolled1 locationNCT06947460
Recruiting
Phase 1Phase 2
Sympathetic Mechanisms in Obesity-Crossover Design
ObesityHypertension
Vanderbilt University Medical Center12 enrolled1 locationNCT05312892
Recruiting
Phase 2
Evaluation of Efficacy and Safety of Iloperidone for the Treatment of Participants With Uncontrolled Hypertension
HypertensionUncontrolled Hypertension
Vanda Pharmaceuticals240 enrolled28 locationsNCT07090161
Recruiting
Phase 2
129 Xenon Imaging in Patients Treated With Sotatercept
Pulmonary HypertensionPulmonary Arterial Hypertension
Bastiaan Driehuys14 enrolled1 locationNCT06351345
Recruiting
Phase 2
129 Xenon MRI as a Biomarker for Diagnosis and Response to Therapy in Pulmonary Arterial Hypertension (PAH)
Pulmonary Arterial HypertensionConnective Tissue DiseasesIdiopathic Pulmonary Arterial Hypertension+1 more
Bastiaan Driehuys20 enrolled1 locationNCT06104228
Recruiting
Phase 2
Pulmonary Hypertension SOLAR
COPDInterstitial Lung DiseasePulmonary Arterial Hypertension
Bastiaan Driehuys30 enrolled1 locationNCT04778046
Recruiting
Phase 2
Endothelin-1 Receptor Blockade in Resistant Hypertension
Resistant Hypertension
University Hospital, Rouen24 enrolled1 locationNCT04388124
Recruiting
Phase 2
Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH
Chronic Obstructive Pulmonary DiseaseDyspneaPulmonary Hypertension
VA Office of Research and Development126 enrolled5 locationsNCT05937854