Phase 3 Hypertension Clinical Trials
51 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 51 trials
Recruiting
Phase 2Phase 3
Study of QLS-111-FDC in Open-Angle Glaucoma or Ocular Hypertension
OAG - Open-Angle GlaucomaOHT - Ocular Hypertension
Qlaris Bio, Inc.36 enrolled1 locationNCT07354516
Recruiting
Phase 3
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
Cardiovascular DiseasesHypertensionDiabetes Mellitus, Type 2
Boehringer Ingelheim11,800 enrolled1153 locationsNCT07064473
Recruiting
Phase 3
A Study Providing Treatment Access in Participants With Pulmonary Hypertension Completing a Parent Study and Having no Other Option
Hypertension, Pulmonary
Actelion280 enrolled43 locationsNCT05179876
Recruiting
Phase 3
LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
Pulmonary Hypertension Associated With HFpEF
Tenax Therapeutics, Inc.540 enrolled92 locationsNCT07288398
Recruiting
Phase 3
A Master Protocol for Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight: (ATTAIN-Hypertension Screening)
Hypertension
Eli Lilly and Company974 enrolled101 locationsNCT06948422
Recruiting
Phase 3
A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)
Pulmonary Arterial Hypertension
Merck Sharp & Dohme LLC815 enrolled63 locationsNCT07218029
Recruiting
Phase 2Phase 3
Sildinafil in Pulmonary Hypertension-Rheumatic Chronic Valvular Disease(RCT)
Pulmonary HypertensionRheumatic Valvular Heart Disease
Sindh Institute of Cardiovascular Diseases100 enrolled1 locationNCT07462260
Recruiting
Phase 3
A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL1
HypertensionOverweight or Obesity
Eli Lilly and Company487 enrolled99 locationsNCT06948435
Recruiting
Phase 3
A Study Comparing the Clinical Benefit of Finerenone Versus a Fixed Dose Combination (FDC) of Extended-Release Torsemide and Spironolactone in Patients With Hypertension and Chronic Kidney Disease
Hypertension (HTN)
Sarfez Pharmaceuticals, Inc.30 enrolled1 locationNCT07223502
Recruiting
Phase 3
A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL2
Hypertension
Eli Lilly and Company487 enrolled99 locationsNCT06952530
Recruiting
Phase 3
Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
Interstitial Lung DiseasePulmonary Hypertension
Insmed Incorporated344 enrolled30 locationsNCT07179380
Recruiting
Phase 3
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
HypertensionHigh Risk Cardiovascular DiseaseHigh Cardiovascular Risk
Alnylam Pharmaceuticals11,000 enrolled229 locationsNCT07181109
Recruiting
Phase 3
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
Chronic Kidney Disease and Hypertension
AstraZeneca5,000 enrolled753 locationsNCT06742723
Recruiting
Phase 3
LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF
Pulmonary Hypertension
Tenax Therapeutics, Inc.230 enrolled44 locationsNCT05983250
Recruiting
Phase 3
Safest Choice of Antihypertensive Regimen for Postpartum Hypertension
Postpartum ComplicationHigh Blood PressureMaternal Hypertension
Loma Linda University500 enrolled1 locationNCT05551104
Recruiting
Phase 3
Efficacy and Safety of HUC3-637 in Patients With Primary Open Angle Glaucoma or Ocular Hypertension
Ocular HypertensionPrimary Open Angle Glaucoma (POAG)
Huons Co., Ltd.206 enrolled1 locationNCT07335211
Recruiting
Phase 3
Tadalafil for Severe Pulmonary Hypertension Due to Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary DiseasePulmonary Hypertension
Assistance Publique - Hôpitaux de Paris200 enrolled1 locationNCT05844462
Recruiting
Phase 3
SGLT2 Inhibition for Cardiovascular Endpoint Reduction in Hypertension
Atrial Hypertension
Prof. Dr. med. Ingo Eitel3,000 enrolled1 locationNCT06804161
Recruiting
Phase 3
Phase 3 Trial to Evaluate the Efficacy and Safety of CKD-202A
Essential Hypertension
Chong Kun Dang Pharmaceutical324 enrolled1 locationNCT06643819
Recruiting
Phase 3
Intensification of Blood Pressure Lowering Therapeutics Based on Diuretics Versus Usual Management for Uncontrolled Hypertension IN Patients With Moderate to Severe Chronic Kidney Disease
Chronic Kidney Disease(CKD)Uncontrolled Hypertension
University Hospital, Tours720 enrolled40 locationsNCT05732727