Phase 1 Lung Cancer Clinical Trials
46 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 46 trials
Recruiting
Phase 1
A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies
Pancreatic CancerLung CancerColon Cancer+3 more
RasCal Therapeutics, Inc.134 enrolled3 locationsNCT04678648
Recruiting
Phase 1Phase 2
A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors
Breast CancerLung Cancer
Bristol-Myers Squibb416 enrolled63 locationsNCT06618287
Recruiting
Phase 1Phase 2
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
Ovarian CancerEndometrial CancerProstate Cancer+5 more
PMV Pharmaceuticals, Inc300 enrolled76 locationsNCT04585750
Recruiting
Phase 1Phase 2
Delayed or Upfront Brain RAdiotherapy in Treatment naïve Lung Cancer Patients With Asymptomatic or Minimally Symptomatic Brain Metastases and ALK rEarrangements
Lung CancerNSCLCBrain Metastases
Joshua Palmer56 enrolled3 locationsNCT05987644
Recruiting
Phase 1
A Study to Test Different Doses of BI 765049 Alone and in Combination With Ezabenlimab in Asian People With Advanced Cancer (Solid Tumours) Positive for B7-H6
Pancreatic CancerLung CancerGastrointestinal Cancer
Boehringer Ingelheim97 enrolled7 locationsNCT06091930
Recruiting
Phase 1
Talazoparib and Thoracic RT for ES-SCLC
Lung Cancer
University Health Network, Toronto24 enrolled1 locationNCT04170946
Recruiting
Phase 1
Preliminary Evaluation of [68Ga]CBP8 in Healthy Individuals, Lung Cancer, and Idiopathic Pulmonary Fibrosis Patients
Lung CancerPulmonary Fibrosis
Massachusetts General Hospital100 enrolled1 locationNCT03535545
Recruiting
Phase 1Phase 2
Carbon Nanoparticle-Loaded Iron in the Treatment of Advanced Solid Tumor
Lung CancerPancreas CancerThyroid Cancer+1 more
Sichuan Enray Pharmaceutical Sciences Company54 enrolled9 locationsNCT07433283
Recruiting
Phase 1
Fluorine-18-AlphaVBeta6-Binding Peptide Positron Emission Tomography in Metastatic Non-Small Cell Lung Cancer
Lung CancerBrain MetastasesLung Cancer Metastatic
University of California, Davis20 enrolled1 locationNCT05452005
Recruiting
Phase 1
A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation
Breast CancerOvarian CancerProstate Cancer+8 more
Clasp Therapeutics, Inc.90 enrolled21 locationsNCT06778863
Recruiting
Phase 1
Binary Oncolytic Adenovirus in Combination With HER2-Specific Autologous CAR VST, Advanced HER2 Positive Solid Tumors
Breast CancerEsophageal CancerGastric Cancer+4 more
Baylor College of Medicine45 enrolled1 locationNCT03740256
Recruiting
Phase 1
Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors
Breast CancerEsophageal CancerGastric Cancer+7 more
SystImmune Inc.280 enrolled17 locationsNCT06293898
Recruiting
Phase 1Phase 2
A First-in-human Study of 3H-10000 in Patients With Unresectable or Metastatic Solid Tumors
Lung CancerStomach Cancer
3H Pharmaceuticals Co., Ltd.170 enrolled1 locationNCT07354711
Recruiting
Phase 1
A Study of Lutetium [177Lu]-BL-ARC001 in Patients With Locally Advanced or Metastatic Lung Cancer, Breast Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors
Breast CancerLung CancerSolid Tumors+1 more
Sichuan Baili Pharmaceutical Co., Ltd.22 enrolled1 locationNCT07274852
Recruiting
Phase 1Phase 2
Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients
Lung CancerNSCLCThoracic Cancer+5 more
Tango Therapeutics, Inc.183 enrolled12 locationsNCT06922591
Recruiting
Phase 1
A Study of GC203 TIL in Advanced Malignant Solid Tumors
Breast CancerLung CancerSolid Tumor+2 more
Shanghai Juncell Therapeutics18 enrolled1 locationNCT06375187
Recruiting
Phase 1Phase 2
VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma
Head and Neck CarcinomaLung CancerAdenoid Cystic Carcinoma
VM Oncology, LLC242 enrolled15 locationsNCT03556228
Recruiting
Phase 1Phase 2
LK101 Combined With PD-1 or PD-L1 Monoclonal Antibody in the Treatment of Lung Cancer
Lung Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences60 enrolled1 locationNCT05886439
Recruiting
Phase 1
VSV-02 Compassionate Use in Advanced Solid Tumors
Breast CancerLung CancerMelanoma+3 more
The First Affiliated Hospital of Xinxiang Medical College6 enrolled1 locationNCT07260591
Recruiting
Phase 1
Fecal Microbiota Transplantation in Treating Immune-Checkpoint Inhibitor Induced-Diarrhea or Colitis in Genitourinary Cancer Patients
Breast CancerOvarian CancerCervical Cancer+6 more
M.D. Anderson Cancer Center40 enrolled1 locationNCT04038619