Phase 2 Lung Cancer Clinical Trials

45 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 45 trials

Recruiting
Phase 2

Study of Novel Treatment Combinations in Patients With Lung Cancer

Lung Cancer
Gilead Sciences270 enrolled100 locationsNCT05633667
Recruiting
Phase 1Phase 2

A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors

Breast CancerLung Cancer
Bristol-Myers Squibb416 enrolled63 locationsNCT06618287
Recruiting
Phase 2

REStoring lymphoCytes Using NKTR-255* After chemoradiothErapy in Solid Tumors (RESCUE)

Lung Cancer
M.D. Anderson Cancer Center39 enrolled1 locationNCT05632809
Recruiting
Phase 1Phase 2

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

Ovarian CancerEndometrial CancerProstate Cancer+5 more
PMV Pharmaceuticals, Inc300 enrolled76 locationsNCT04585750
Recruiting
Phase 2Phase 3

Study of CTDNA Response Adaptive Immuno-Chemotherapy in Lung Cancer

Lung Cancer
Canadian Cancer Trials Group230 enrolled10 locationsNCT04093167
Recruiting
Phase 2

Reducing Respiratory Symptoms of Pulmonary Irradiation in Interstitial Lung Disease

Lung CancerInterstitial Lung Disease
David Palma98 enrolled3 locationsNCT05986318
Recruiting
Phase 1Phase 2

Delayed or Upfront Brain RAdiotherapy in Treatment naïve Lung Cancer Patients With Asymptomatic or Minimally Symptomatic Brain Metastases and ALK rEarrangements

Lung CancerNSCLCBrain Metastases
Joshua Palmer56 enrolled3 locationsNCT05987644
Recruiting
Phase 2

Riluzole For Preventing Cognitive Dysfunction in Ca Pts Receiving Chemo (REFOCUS): Pilot Trial

Breast CancerSarcomaLung Cancer+2 more
University of California, Irvine24 enrolled1 locationNCT07447050
Recruiting
Phase 2

Evaluation of PET Probe [68Ga]CBP8 in the Detection of Radiation Induced Tissue Injury

Lung CancerPancreas CancerRadiation Fibrosis+1 more
Massachusetts General Hospital72 enrolled1 locationNCT04485286
Recruiting
Phase 1Phase 2

Carbon Nanoparticle-Loaded Iron in the Treatment of Advanced Solid Tumor

Lung CancerPancreas CancerThyroid Cancer+1 more
Sichuan Enray Pharmaceutical Sciences Company54 enrolled9 locationsNCT07433283
Recruiting
Phase 2

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

Breast CancerEsophageal CancerGastric Cancer+11 more
Daiichi Sankyo740 enrolled84 locationsNCT06172478
Recruiting
Phase 1Phase 2

A First-in-human Study of 3H-10000 in Patients With Unresectable or Metastatic Solid Tumors

Lung CancerStomach Cancer
3H Pharmaceuticals Co., Ltd.170 enrolled1 locationNCT07354711
Recruiting
Phase 2

A Trial of HRS-4508 Combined With Other Antitumor Therapies in Subjects With Locally Advanced or Metastatic Non-small Cell Lung Cancer

Lung Cancer
Jiangsu HengRui Medicine Co., Ltd.100 enrolled2 locationsNCT07232849
Recruiting
Phase 1Phase 2

Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients

Lung CancerNSCLCThoracic Cancer+5 more
Tango Therapeutics, Inc.183 enrolled12 locationsNCT06922591
Recruiting
Phase 2Phase 3

Trop2-targeted immunoPET Imaging of Solid Tumors

Liver CancerOvarian CancerCervical Cancer+11 more
RenJi Hospital400 enrolled1 locationNCT06851663
Recruiting
Phase 1Phase 2

LK101 Combined With PD-1 or PD-L1 Monoclonal Antibody in the Treatment of Lung Cancer

Lung Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences60 enrolled1 locationNCT05886439
Recruiting
Phase 2

A Phase II Clinical Study of FH-006 for Injection Combined With Other Anticancer Therapies in Subjects With Lung Cancer

Lung Cancer
Jiangsu HengRui Medicine Co., Ltd.200 enrolled1 locationNCT07241767
Recruiting
Phase 2

Adding Certolizumab to Chemotherapy + Nivolumab in People Who Have Lung Cancer That Can Be Treated With Surgery

Lung CancerLung Cancer Stage IILung Cancer Stage III
Memorial Sloan Kettering Cancer Center60 enrolled7 locationsNCT04991025
Recruiting
Phase 1Phase 2

A Study of Valemetostat Tosylate Plus Pembrolizumab Versus Pembrolizumab Alone in First-Line NSCLC Without Actionable Genomic Alterations

Lung CancerNon-small Cell Lung Cancer
Daiichi Sankyo137 enrolled45 locationsNCT06644768
Recruiting
Phase 2

A Single Arm, Phase 2 Study of Datopotamab Deruxtecan, Carboplatin, and Pembrolizumab for Treatment-naive Brain Metastases From NSCLC (Non-small Cell Lung Cancer)

Lung Cancer
Latin American Cooperative Oncology Group46 enrolled1 locationNCT06822543