Phase 2 Metastatic Cancer Clinical Trials
10 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–10 of 10 trials
Recruiting
Phase 1Phase 2
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
Ovarian CancerEndometrial CancerProstate Cancer+5 more
PMV Pharmaceuticals, Inc300 enrolled76 locationsNCT04585750
Recruiting
Phase 1Phase 2
Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer
Advanced Solid TumorMetastatic CancerCutaneous Melanoma
Aulos Bioscience, Inc.159 enrolled17 locationsNCT05267626
Recruiting
Phase 2
Trial of Two Adagrasib Dosing Regimens in NSCLC With KRAS G12C Mutation (KRYSTAL 21)
Metastatic CancerAdvanced CancerMalignant Neoplasm of Lung
Mirati Therapeutics Inc.200 enrolled120 locationsNCT05853575
Recruiting
Phase 2
Study of Cabozantinib and Nivolumab in Metastatic Castration Resistant Prostate Cancer
Metastatic CancerCastration-resistant Prostate Cancer
Rana McKay, MD47 enrolled4 locationsNCT05502315
Recruiting
Phase 1Phase 2
Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer
Breast CancerBreast Cancer MetastaticOvarian Cancer+6 more
Incyclix Bio150 enrolled17 locationsNCT05735080
Recruiting
Phase 2
Definitive Radiation for High-Risk Spine Metastases
Metastatic Breast CancerMetastatic CancerMetastatic Lung Cancer+5 more
Stony Brook University26 enrolled1 locationNCT06165419
Recruiting
Phase 2
Biomarkers to Detect Endocrine Therapy Resistance
Breast CancerMetastatic CancerLobular Breast Carcinoma
University of Wisconsin, Madison8 enrolled1 locationNCT06067503
Recruiting
Phase 2
COntinue the SaMe Systemic Therapy After Local Ablative Therapy for Oligo Progression in Metastatic Breast Cancer - the COSMO Study
Breast Cancer InvasiveMetastatic CancerOligoprogressive
The Netherlands Cancer Institute118 enrolled7 locationsNCT05301881
Recruiting
Phase 1Phase 2
A Study of OR502, a Monoclonal Antibody Targeting LILRB2, Alone and in Combination With Anticancer Agents
Advanced Solid TumorCancerNon-small Cell Lung Cancer+4 more
OncoResponse, Inc.168 enrolled4 locationsNCT06090266
Recruiting
Phase 2
Immune Therapy in HR-positive/HER2-negative Metastatic Breast Cancer(ENIGMA)-BCTOP-L-M02
Breast CancerMetastatic Cancer
Fudan University338 enrolled1 locationNCT05205200